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Titolo:
Diva vaccines that reduce virus transmission
Autore:
van Oirschot, JT;
Indirizzi:
Inst Anim Sci & Hlth, Dept Mammalian Virol, NL-8200 AB Lelystad, Netherlands Inst Anim Sci & Hlth Lelystad Netherlands NL-8200 AB lystad, Netherlands
Titolo Testata:
JOURNAL OF BIOTECHNOLOGY
fascicolo: 2-3, volume: 73, anno: 1999,
pagine: 195 - 205
SICI:
0168-1656(19990820)73:2-3<195:DVTRVT>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
VIRAL DIARRHEA VIRUS; AUJESZKYS-DISEASE PSEUDORABIES; NONSTRUCTURAL PROTEIN NS1; BOVINE HERPESVIRUS-1 INFECTIONS; E-NEGATIVE STRAIN; GLYCOPROTEIN-E; MARKER VACCINES; INACTIVATED VACCINE; PIG-POPULATIONS; HOG-CHOLERA;
Keywords:
diva vaccines; virus transmission; swine and cattle;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
69
Recensione:
Indirizzi per estratti:
Indirizzo: van Oirschot, JT Inst Anim Sci & Hlth, Dept Mammalian Virol, POB 65, NL-8200 AB Lelystad, Netherlands Inst Anim Sci & Hlth POB 65 Lelystad Netherlands NL-8200 AB
Citazione:
J.T. van Oirschot, "Diva vaccines that reduce virus transmission", J BIOTECH, 73(2-3), 1999, pp. 195-205

Abstract

This brief review deals with the effect of diva (Differentiating Infected from VAccinated individuals) vaccines (also termed marl;er vaccines) on transmission of herpesviruses and pestiviruses in swine and cattle. Pseudorabies and bovine herpesvirus 1 diva vaccines have been demonstrated to reduce transmission of wild-type virus in populations of pigs and cattle in the laboratory as well as in the field. A subunit diva vaccine based on the immunodominant E2 protein of classical swine fever virus that is expressed in the baculovirus system may reduce transmission of wild-type virus among pigs and also transmission from mother to foetuses. A similar diva vaccine against bovine virus diarrhoea infections protected sheep against transplacentaltransmission of antigenically homologous wild-type virus. Diva vaccines along with their companion diagnostic tests can play a role in control of infections: ultimately leading to eradication of viruses, (C) 1999 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 17:23:45