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Titolo:
Bone marrow transplantation for children with acquired or congenital marrow failure
Autore:
Camitta, BM;
Indirizzi:
Med Coll Wisconsin, Midwest Childrens Canc Ctr, MACC Fund Res Ctr, Dept Pediat, Milwaukee, WI 53226 USA Med Coll Wisconsin Milwaukee WI USA 53226 Pediat, Milwaukee, WI 53226 USA Childrens Hosp Wisconsin, Milwaukee, WI 53201 USA Childrens Hosp Wisconsin Milwaukee WI USA 53201 , Milwaukee, WI 53201 USA
Titolo Testata:
INTERNATIONAL JOURNAL OF PEDIATRIC HEMATOLOGY/ONCOLOGY
fascicolo: 4, volume: 6, anno: 1999,
pagine: 283 - 290
SICI:
1070-2903(1999)6:4<283:BMTFCW>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEVERE APLASTIC-ANEMIA; VERSUS-HOST DISEASE; HLA-IDENTICAL SIBLINGS; TERM FOLLOW-UP; SOLID MALIGNANT-TUMORS; SAA WORKING PARTY; ANTITHYMOCYTE GLOBULIN; YOUNG-ADULTS; RISK-FACTORS; GRAFT;
Keywords:
bone marrow transplantation; aplastic anemia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
50
Recensione:
Indirizzi per estratti:
Indirizzo: Camitta, BM Med Coll Wisconsin, Midwest Childrens Canc Ctr, MACC Fund Res Ctr, Dept Pediat, 8701 Watertown Plank Rd, Milwaukee, WI 53226 USA Med CollWisconsin 8701 Watertown Plank Rd Milwaukee WI USA 53226
Citazione:
B.M. Camitta, "Bone marrow transplantation for children with acquired or congenital marrow failure", INT J PED H, 6(4), 1999, pp. 283-290

Abstract

Bone marrow failure in children may result from congenital or acquired diseases. Regardless of the etiology, prognosis depends upon the severity of impairment of hematopoiesis. With supportive care alone, 80% of patients with acquired severe marrow failure used to die of bleeding, infection or other complications (Camitta et al., 1976, Blood, 48, 63-70). Recently, both bone marrow transplantation, granulocyte colony stimulating factors and immunosuppression have greatly improved the outcome of children with marrow failure. This paper reviews the current status of bone marrow transplantation for the treatment of children with severe aplastic anemia and related disorders. Recommendations are made regarding the optimal timing of marrow transplantation in regard to the severity of disease and the availability of a related or unrelated marrow donor.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 06:26:31