Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Cardiovascular afferent signals and drinking in response to hypotension indogs
Autore:
Thrasher, TN; Keenan, CR; Ramsay, DJ;
Indirizzi:
Univ Maryland, Dept Surg, Baltimore, MD 21201 USA Univ Maryland BaltimoreMD USA 21201 , Dept Surg, Baltimore, MD 21201 USA Univ Maryland, Dept Physiol, Baltimore, MD 21201 USA Univ Maryland Baltimore MD USA 21201 ept Physiol, Baltimore, MD 21201 USA Dept Vet Affairs, Santa Rosa, CA 95404 USA Dept Vet Affairs Santa Rosa CAUSA 95404 ffairs, Santa Rosa, CA 95404 USA
Titolo Testata:
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
fascicolo: 3, volume: 46, anno: 1999,
pagine: R795 - R801
SICI:
0363-6119(199909)46:3<R795:CASADI>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONSCIOUS DOGS; PLASMA VASOPRESSIN; RENIN RELEASE; ARTERIAL BARORECEPTORS; VENOUS RETURN; PRESSURE; HEMORRHAGE; RECEPTORS; CORTISOL; HEART;
Keywords:
arterial baroreceptors; cardiac receptors; atrial receptors; blood volume; hypovolemia; renin-angiotensin system;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Thrasher, TN Univ Maryland, Dept Surg, 10 S Pine St,Rm 400, Baltimore, MD 21201 USA Univ Maryland 10 S Pine St,Rm 400 Baltimore MD USA 21201 USA
Citazione:
T.N. Thrasher et al., "Cardiovascular afferent signals and drinking in response to hypotension indogs", AM J P-REG, 46(3), 1999, pp. R795-R801

Abstract

Arterial hypotension stimulates increases in plasma arginine vasopressin (AVP), plasma renin activity (PRA), and water intake in conscious dogs. We have previously reported that increasing left atrial but not right atrial pressure completely blocks the increase in plasma AVP and PRA induced by hypotension. The goal of the present study was to examine the effect of increasing right or left atrial pressure on water intake induced by arterial hypotension. Dogs were prepared with occluding cuffs on the thoracic inferior vena cava, the pulmonary artery, and the ascending aorta. We reduced mean arterial pressure (MAP) 25% below control by either inferior vena cava constriction (IVCC), pulmonary artery constriction (PAC), or ascending aorta constriction (AAC) and measured water intake over a 2-h period. Cumulative waterintake during IVCC (n = 6) and PAC (n = 6) was 7.8 +/- 2.0 and 6.7 +/- 2.6ml/kg, respectively. There was no difference between either the latency orthe volume consumed between the two treatments. In contrast, none of the dogs drank during hypotension induced by AAC (n = 5). Because the degree of arterial baroreceptor unloading was the same in each treatment by design, we conclude that stimulation of left atrial receptors inhibits drinking in response to arterial hypotension but that stimulation of right atrial receptors has no effect on the response in dogs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 11:02:36