Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Cardiovascular disease in older adults with glucose disorders: comparison of American Diabetes Association criteria for diabetes mellitus with WHO criteria
Autore:
Barzilay, JI; Spiekerman, CF; Wahl, PW; Kuller, LH; Cushman, M; Furberg, CD; Dobs, A; Polak, JF; Savage, PJ;
Indirizzi:
Kaiser Permanente Georgia, Div Endocrinol, Tucker, GA 30084 USA Kaiser Permanente Georgia Tucker GA USA 30084 rinol, Tucker, GA 30084 USA Emory Univ, Sch Med, Div Endocrinol, Atlanta, GA USA Emory Univ Atlanta GA USA Univ, Sch Med, Div Endocrinol, Atlanta, GA USA Univ Washington, Dept Biostat, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 Dept Biostat, Seattle, WA 98195 USA Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA USA Univ Pittsburgh Pittsburgh PA USA th, Dept Epidemiol, Pittsburgh, PA USA Univ Vermont, Sch Med, Dept Med, Colchester, VT USA Univ Vermont Colchester VT USA nt, Sch Med, Dept Med, Colchester, VT USA Wake Forest Univ, Bowman Gray Sch Med, Dept Publ Hlth Sci, Winston Salem, NC 27103 USA Wake Forest Univ Winston Salem NC USA 27103 , Winston Salem, NC 27103 USA Johns Hopkins Univ, Sch Med, Div Endocrinol, Baltimore, MD USA Johns Hopkins Univ Baltimore MD USA d, Div Endocrinol, Baltimore, MD USA Brigham & Womens Hosp, Dept Radiol, Boston, MA 02115 USA Brigham & Womens Hosp Boston MA USA 02115 pt Radiol, Boston, MA 02115 USA NHLBI, Div Epidemiol & Clin Applicat, Bethesda, MD 20892 USA NHLBI Bethesda MD USA 20892 emiol & Clin Applicat, Bethesda, MD 20892 USA
Titolo Testata:
LANCET
fascicolo: 9179, volume: 354, anno: 1999,
pagine: 622 - 625
SICI:
0140-6736(19990821)354:9179<622:CDIOAW>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEALTH;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
13
Recensione:
Indirizzi per estratti:
Indirizzo: Barzilay, JI Kaiser Permanente Georgia, Div Endocrinol, 200 Crescent Ctr Pkwy, Tucker, GA 30084 USA Kaiser Permanente Georgia 200 Crescent Ctr Pkwy Tucker GA USA 30084
Citazione:
J.I. Barzilay et al., "Cardiovascular disease in older adults with glucose disorders: comparison of American Diabetes Association criteria for diabetes mellitus with WHO criteria", LANCET, 354(9179), 1999, pp. 622-625

Abstract

Background The new fasting American Diabetes Association (ADA) criteria for the diagnosis of diabetes mellitus rely mainly on fasting blood glucose concentrations and use a lower cutoff value for diagnosis than the WHO criteria. We aimed to assess the sensitivity of these criteria for the detectionof cardiovascular disease, the main complication of diabetes mellitus in the elderly. Methods We did a cross-sectional and prospective analysis of 4515 participants of the Cardiovascular Health Study, an 8-year longitudinal study designed to identify factors related to the onset and course of cardiovascular disease in adults aged at least 65 years. We calculated the prevalence and incidence of cardiovascular disease for the ADA and WHO criteria. Findings There was a higher prevalence of cardiovascular disease among individuals with impaired glucose or newly diagnosed diabetes by both criteriathan among those with normal glucose concentrations. However, because fewer individuals had abnormal glucose states by the fasting ADA criteria (22.3%) than by the WHO criteria (46.8%), the number of cases of cardiovascular disease attributable to abnormal glucose stales was a third of that attributable by the WHO criteria (53 vs 159 cases per 10 000), For the two sets ofcriteria, the relative risk for incident cardiovascular disease (mean follow-up 5.9 years) was higher in individuals with impaired glucose and newly diagnosed diabetes than in those with normal glucose. Individuals classified as normal by the fasting ADA criteria had a higher absolute number of incident events (455 of 581 events) than those classified as normal by the WHOcriteria (269 of 581 events). Fasting ADA criteria were therefore less sensitive than the WHO criteria for predicting cardiovascular disease among individuals with abnormal glucose (sensitivity, 28% vs 54%),Interpretation The new fasting ADA criteria seem to be less predictive than the WHO criteria for the burden of cardiovascular disease associated withabnormal glucose in the elderly.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 06:00:26