Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Synthesis of an asparagine-linked core pentasaccharide by means of simultaneous inversion reactions
Autore:
Matsuo, I; Isomura, M; Ajisaka, K;
Indirizzi:
Meiji Milk Prod Co Ltd, Meiji Inst Hlth Sci, Odawara, Kanagawa 2500862, Japan Meiji Milk Prod Co Ltd Odawara Kanagawa Japan 2500862 gawa 2500862, Japan
Titolo Testata:
JOURNAL OF CARBOHYDRATE CHEMISTRY
fascicolo: 7, volume: 18, anno: 1999,
pagine: 841 - 850
SICI:
0732-8303(1999)18:7<841:SOAACP>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
BETA-D-GALACTOSIDE; PROMOTED REACTIONS; GLYCOPEPTIDES; OLIGOSACCHARIDES; GLYCOSIDES; CHAINS; UNITS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Ajisaka, K Meiji Milk Prod Co Ltd, Meiji Inst Hlth Sci, 540 Naruda, Odawara, Kanagawa2500862, Japan Meiji Milk Prod Co Ltd 540 Naruda Odawara Kanagawa Japan 2500862
Citazione:
I. Matsuo et al., "Synthesis of an asparagine-linked core pentasaccharide by means of simultaneous inversion reactions", J CARB CHEM, 18(7), 1999, pp. 841-850

Abstract

A novel route for the synthesis of the asparagine-linked pentasaccharide 1, the core unit of all asparagine-linked sugar chains, is described. To construct this pentasaccharide derivative, we first employed a regioselective coupling of a mannosyl donor to the C-3 and C-6 positions of a galactosyl chitobiose acceptor, and then by means of a conversion involving two simultaneous inversion reactions of the stereochemistry of the C-2 and C-4 hydroxyl groups of a galactose residue, a branched pentasaccharide containing the difficult to synthesize beta-mannose unit was easily obtained.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 12:02:01