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Titolo:
Intraoperative probes and imaging probes
Autore:
Hoffman, EJ; Tornai, MP; Janecek, R; Patt, BE; Iwanczyk, JS;
Indirizzi:
Univ Calif Los Angeles, Sch Med, Dept Pharmacol, Div Nucl Med, Los Angeles, CA 90095 USA Univ Calif Los Angeles Los Angeles CA USA 90095 Los Angeles, CA 90095 USA Duke Univ, Med Ctr, Dept Radiol, Durham, NC 27710 USA Duke Univ Durham NCUSA 27710 Med Ctr, Dept Radiol, Durham, NC 27710 USA Photon Imaging Inc, Northridge, CA USA Photon Imaging Inc Northridge CA USA ton Imaging Inc, Northridge, CA USA
Titolo Testata:
EUROPEAN JOURNAL OF NUCLEAR MEDICINE
fascicolo: 8, volume: 26, anno: 1999,
pagine: 913 - 935
SICI:
0340-6997(199908)26:8<913:IPAIP>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
SENTINEL LYMPH-NODE; RADIOLABELED MONOCLONAL-ANTIBODY; RADIOIMMUNOGUIDED SURGERY RIGS; IMPLANTED-SILICON DETECTORS; EARLY-STAGE MELANOMA; GAMMA-PROBE; COLORECTAL-CANCER; BREAST-CANCER; MALIGNANT-MELANOMA; TUMOR-LOCALIZATION;
Keywords:
intraoperative probes; sentinel node detection;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
164
Recensione:
Indirizzi per estratti:
Indirizzo: Hoffman, EJ Univ Calif Los Angeles, Sch Med, Dept Pharmacol, Div Nucl Med,10833 Le Conte Ave, Los Angeles, CA 90095 USA Univ Calif Los Angeles 10833Le Conte Ave Los Angeles CA USA 90095
Citazione:
E.J. Hoffman et al., "Intraoperative probes and imaging probes", EUR J NUCL, 26(8), 1999, pp. 913-935

Abstract

Intraoperative probes have been employed to assist in the detection and removal of tumors for more than 50 years, For a period of about 40 years, essentially every detector type that could be miniaturized had been tested or at least suggested for use as an intraoperative probe. These detectors included basic Geiger-Muller (GM) tubes, scintillation detectors, and even state-of-the - art solid state detectors. The radiopharmaceuticals have progressed from (PO4)-P-32- injections for brain tumors to sophisticated monoclonal antibodies labeled with iodine-125 for colorectal cancers. The early workwas mostly anecdotal, primarily interdisciplinary collaborations between surgeons and physical scientists. These collaborations produced a few publications, but never seemed to result in an ongoing clinical practice. In the mid 1980s, several companies offered basic gamma-detecting intraoperative probes as products. This led to the rapid development of radioimmunoguided surgery (RIGS) and sentinel node detection as regularly practiced proceduresto assist in the diagnosis and treatment of cancer. In recent years intraoperative imaging probes have been developed. These devices add the ability to see the details of the detected activity, giving the potential of using the technique in a low-contrast environment. Intraoperative probes are now established as clinical devices, they have a commercial infrastructure to support their continued use, and there is ongoing research, both commercial and academic, that would seem to ensure continued progress and renewed interest in this slowly developing field.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 19:46:29