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Titolo:
Pulsatile hemodynamics in hypertension
Autore:
Mitchell, GF; Pfeffer, MA;
Indirizzi:
Cardiovasc Engn Inc, Dover, MA 02030 USA Cardiovasc Engn Inc Dover MA USA02030 vasc Engn Inc, Dover, MA 02030 USA
Titolo Testata:
CURRENT OPINION IN CARDIOLOGY
fascicolo: 5, volume: 14, anno: 1999,
pagine: 361 - 369
SICI:
0268-4705(199909)14:5<361:PHIH>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
ISOLATED SYSTOLIC HYPERTENSION; LEFT-VENTRICULAR HYPERTROPHY; CONVERTING-ENZYME-INHIBITION; PULSE PRESSURE; BLOOD-PRESSURE; MYOCARDIAL-INFARCTION; CARDIAC-HYPERTROPHY; AORTIC COMPLIANCE; ELDERLY PATIENTS; CARDIOVASCULAR MORTALITY;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
69
Recensione:
Indirizzi per estratti:
Indirizzo: Mitchell, GF Cardiovasc Engn Inc, 3 Draper Rd, Dover, MA 02030 USA Cardiovasc Engn Inc 3 Draper Rd Dover MA USA 02030 02030 USA
Citazione:
G.F. Mitchell e M.A. Pfeffer, "Pulsatile hemodynamics in hypertension", CURR OPIN C, 14(5), 1999, pp. 361-369

Abstract

The hemodynamics of hypertension and antihypertensive therapy have generally been approached in terms of the steady-flow load on the heart. Recent evidence, however, suggests that the pulsatile component of hemodynamic load may play a fundamental role in both the development and progression of hypertensive cardiovascular disease and its clinical sequelae, Pulse pressure, a correlate of conduit vessel stiffness, has been shown to be an important independent predictor of clinical events in hypertensive patients and in the general population. Unrecognized effects on pulsatile hemodynamics may account for the differential effects of various agents on left ventricular mass and events. A better understanding of abnormalities in pulsatile load inhypertension will facilitate risk stratification in and treatment of patients with hypertension, Curr Opin Cardiol 1999, 14:361-369 (C) 1999 Lippincott Williams & Wilkins. Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 06:47:22