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Titolo:
Number of neurons in the retinal ganglion cell layer of the quokka wallabydo not change throughout life
Autore:
Harman, AM; Moore, S;
Indirizzi:
Univ Western Australia, Dept Psychol, Nedlands, WA 6097, Australia Univ Western Australia Nedlands WA Australia 6097 nds, WA 6097, Australia
Titolo Testata:
ANATOMICAL RECORD
fascicolo: 1, volume: 256, anno: 1999,
pagine: 78 - 83
SICI:
0003-276X(19990901)256:1<78:NONITR>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN OPTIC-NERVE; MARSUPIAL SETONIX-BRACHYURUS; PIGMENT EPITHELIUM; FIBER POPULATION; AREA CENTRALIS; VISUAL STREAK; RHESUS-MONKEY; TOPOGRAPHY; AGE; RPE;
Keywords:
marsupial; aging; retina; cell death; cell counting; ganglion cell; morphology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Harman, AM Univ Western Australia, Dept Psychol, Nedlands, WA 6097, Australia Univ Western Australia Nedlands WA Australia 6097 7, Australia
Citazione:
A.M. Harman e S. Moore, "Number of neurons in the retinal ganglion cell layer of the quokka wallabydo not change throughout life", ANAT REC, 256(1), 1999, pp. 78-83

Abstract

During adult life, the topography of the retinal pigment epithelium (RPE) of the quokka wallaby changes gradually. Cells in peripheral retina enlargein surface area while those in mid-temporal retina, adjacent to the area centralis, a high density region in the ganglion cell layer, decrease in area, implying that the tissue in this area is drawing together. We speculatedthat high ganglion cell densities in temporal regions might be maintained,in the face of cell loss due to aging, by this apparent drawing together of the RPE sheet. Therefore, we examined the retinal ganglion cell layer of the quokka in cresyl violet stained wholemounts from animals aged from 0.55to 13.5 years. We found that total neuron number in the retinal ganglion cell layer of the quokka did not decrease significantly throughout life eventhough individuals in captivity live long lives (9-15 years). Ganglion andamacrine cells were counted separately and identified by strict morphological criteria. Nevertheless, the proportion of ganglion to amacrine cells appeared to decrease linearly throughout life, indicating that the morphologyof a proportion of neurons became more amacrine-like during aging. Mean cell size did not change throughout life. In the quokka, retinal area increases slowly throughout life and may account for the small reduction in cell density seen in most retinal regions. Anat Rec 256:78-83, 1999. (C) 1999 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/10/20 alle ore 03:27:07