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Titolo:
Altered parallel auditory processing in schizophrenia patients
Autore:
Pekkonen, E; Huotilainen, M; Katila, H; Karhu, J; Naatanen, R; Tuhonen, J;
Titolo Testata:
SCHIZOPHRENIA BULLETIN
fascicolo: 3, volume: 25, anno: 1999,
pagine: 601 - 607
SICI:
0586-7614(1999)25:3<601:APAPIS>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
EVOKED MAGNETIC-FIELDS; EVENT-RELATED POTENTIALS; MIDDLE-LATENCY; HUMAN-BRAIN; ABNORMALITIES; DYSFUNCTION; HEMISPHERE; DISEASE;
Keywords:
magnetoencephalography; event-related potentials; P50; N100; schizophrenia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Life Sciences
Citazioni:
36
Recensione:
Indirizzi per estratti:
Citazione:
E. Pekkonen et al., "Altered parallel auditory processing in schizophrenia patients", SCHIZO BULL, 25(3), 1999, pp. 601-607

Abstract

Patients with schizophrenia have impaired auditory processing that has been demonstrated by diminished P50 response to paired auditory stimuli in event-related potential (ERP) studies, Cerebral processing can also be studiedwith magnetoencephalography (MEG), With a whole-head MEG, which enables one to simultaneously measure brain activity in both hemispheres, we investigated whether early parallel auditory processing is impaired in schizophrenia. Sequences of tones were monaurally presented to schizophrenia patients and healthy controls in a passive condition, and the event-related magnetic fields were recorded simultaneously over both auditory cortices, The interhemispheric latency difference of the P50m, but not that of the N100m, was significantly shorter in the patient group in the right-ear but not in the left-ear stimulus condition. Further, the ipsilateral P50m was significantlyearlier in schizophrenia patients in the right-ear condition. This result suggests that schizophrenia affects the consecutive preconscious auditory processing in a different manner.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/20 alle ore 07:01:52