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Titolo:
Virulence of Mycobacterium tuberculosis CDC1551 and H37Rv in rabbits evaluated by Lurie's pulmonary tubercle count method
Autore:
Bishai, WR; Dannenberg, AM; Parrish, N; Ruiz, R; Chen, P; Zook, BC; Johnson, W; Boles, JW; Pitt, MLM;
Indirizzi:
Johns Hopkins Univ, Sch Hyg & Publ Hlth, Dept Environm Hlth Sci, Baltimore, MD USA Johns Hopkins Univ Baltimore MD USA Environm Hlth Sci, Baltimore, MD USA Johns Hopkins Univ, Sch Hyg & Publ Hlth, Dept Mol Microbiol & Immunol, Baltimore, MD USA Johns Hopkins Univ Baltimore MD USA crobiol & Immunol, Baltimore, MD USA Johns Hopkins Univ, Sch Hyg & Publ Hlth, Dept Int Hlth, Baltimore, MD USA Johns Hopkins Univ Baltimore MD USA th, Dept Int Hlth, Baltimore, MD USA Johns Hopkins Univ, Sch Hyg & Publ Hlth, Dept Epidemiol, Baltimore, MD USAJohns Hopkins Univ Baltimore MD USA h, Dept Epidemiol, Baltimore, MD USA Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD 21205 USA Johns Hopkins Univ Baltimore MD USA 21205 pt Med, Baltimore, MD 21205 USA Johns Hopkins Univ, Sch Med, Dept Pathol, Baltimore, MD 21205 USA Johns Hopkins Univ Baltimore MD USA 21205 Pathol, Baltimore, MD 21205 USA George Washington Univ, Med Ctr, Dept Pathol, Washington, DC 20037 USA George Washington Univ Washington DC USA 20037 , Washington, DC 20037 USA George Washington Univ, Med Ctr, Dept Anim Res, Washington, DC 20037 USA George Washington Univ Washington DC USA 20037 , Washington, DC 20037 USA USA, Dept Aerobiol & Prod Evaluat, Med Res Inst Infect Dis, Frederick, MD USA USA Frederick MD USA Evaluat, Med Res Inst Infect Dis, Frederick, MD USA
Titolo Testata:
INFECTION AND IMMUNITY
fascicolo: 9, volume: 67, anno: 1999,
pagine: 4931 - 4934
SICI:
0019-9567(199909)67:9<4931:VOMTCA>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
DELAYED-TYPE HYPERSENSITIVITY; CELL-MEDIATED-IMMUNITY; PATHOGENESIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Dannenberg, AM Johns Hopkins Sch Hyg, 615 N Wolfe St, Baltimore, MD 21205 USA Johns Hopkins Sch Hyg 615 N Wolfe St Baltimore MD USA 21205
Citazione:
W.R. Bishai et al., "Virulence of Mycobacterium tuberculosis CDC1551 and H37Rv in rabbits evaluated by Lurie's pulmonary tubercle count method", INFEC IMMUN, 67(9), 1999, pp. 4931-4934

Abstract

The virulence of the CDC1551 strain of Mycobacterium tuberculosis was compared to that of H37Rv in a rabbit inhalation model. While rabbits that inhaled the two strains produced equal numbers of grossly visible primary tubercles, CDC1551 tubercles were smaller and contained fewer bacilli than H37Rvtubercles. These findings suggest that a miniepidemic near the Kentucky-Tennessee border caused by CDC1551 was due not to increased virulence but to increased transmissibility.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 19:20:20