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Titolo:
Effects of reducing submandibular blood flow on secretory responses to parasympathetic stimulation in anaesthetized cats
Autore:
Hanna, SJ; Brelen, ME; Edwards, AV;
Indirizzi:
Univ Cambridge, Physiol Lab, Cambridge CB2 3EG, England Univ Cambridge Cambridge England CB2 3EG Lab, Cambridge CB2 3EG, England
Titolo Testata:
EXPERIMENTAL PHYSIOLOGY
fascicolo: 4, volume: 84, anno: 1999,
pagine: 677 - 687
SICI:
0958-0670(199907)84:4<677:EORSBF>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
VASOACTIVE-INTESTINAL-PEPTIDE; RAT PAROTID-GLAND; NITRIC-OXIDE; VASODILATOR RESPONSES; PROTEIN SECRETION; CELL-VOLUME; BURSTS; INVIVO;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Edwards, AV Univ Cambridge, Physiol Lab, Downing St, Cambridge CB2 3EG, England Univ Cambridge Downing St Cambridge England CB2 3EG , England
Citazione:
S.J. Hanna et al., "Effects of reducing submandibular blood flow on secretory responses to parasympathetic stimulation in anaesthetized cats", EXP PHYSIOL, 84(4), 1999, pp. 677-687

Abstract

Submandibular secretory responses to stimulation of the parasympathetic chorda-lingual nerve were investigated in five anaesthetized cats before, during and after withdrawal of blood (ca 20 ml kg(-1)) in order to investigatethe consequences of a reduced blood flow through the gland. Stimulation atdifferent frequencies (2, 4, 6 and 8 Hz) evoked a frequency-dependent increase in the now of submandibular saliva, sodium concentration, electrolyte and protein output. When the blood pressure was reduced (by about 50 %) there was a significant reduction in submandibular blood flow and the secretion of both saliva and protein during stimulation. Under each set of conditions the flow of saliva was linearly related to the blood flow through the gland. IL is concluded that submandibular secretory responses to electrical stimulation of the parasympathetic innervation can be significantly attenuated when the blood flow through the gland is reduced under the conditions employed in this study.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 13:44:50