Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
BRAIN 5-HYDROXYTRYPTAMINE UPTAKE SITES LABELED WITH [H-3] PAROXETINE IN ANTIDEPRESSANT DRUG-TREATED DEPRESSED SUICIDE VICTIMS AND CONTROLS
Autore:
LAWRENCE KM; DEPAERMENTIER F; LOWTHER S; CROMPTON MR; KATONA CLE; HORTON RW;
Indirizzi:
ST GEORGE HOSP,SCH MED,DEPT PHARMACOL & CLIN PHARMACOL LONDON SW17 0RE ENGLAND ST GEORGE HOSP,SCH MED,DEPT PHARMACOL & CLIN PHARMACOL LONDON SW17 0RE ENGLAND ST GEORGE HOSP,SCH MED,DEPT FORENS MED LONDON SW17 0RE ENGLAND UNIV COLL LONDON,SCH MED,DEPT PSYCHIAT LONDON W1N 8AA ENGLAND
Titolo Testata:
Journal of psychiatry & neuroscience
fascicolo: 3, volume: 22, anno: 1997,
pagine: 185 - 191
SICI:
1180-4882(1997)22:3<185:B5USLW>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
H-3 PAROXETINE BINDING; 5-HT UPTAKE SITES; SEROTONIN UPTAKE; IMIPRAMINE BINDING; BLOOD-PLATELETS; RAT-BRAIN; H-3-IMIPRAMINE BINDING; CORTICAL MEMBRANES; MAJOR DEPRESSION; FRONTAL-CORTEX;
Keywords:
5-HYDROXYTRYPTAMINE (5-HT) UPTAKE SITES; [H-3] PAROXETINE BINDING; POSTMORTEM HUMAN BRAIN; DEPRESSION; SUICIDE; ANTIDEPRESSANT DRUGS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Citazioni:
38
Recensione:
Indirizzi per estratti:
Citazione:
K.M. Lawrence et al., "BRAIN 5-HYDROXYTRYPTAMINE UPTAKE SITES LABELED WITH [H-3] PAROXETINE IN ANTIDEPRESSANT DRUG-TREATED DEPRESSED SUICIDE VICTIMS AND CONTROLS", Journal of psychiatry & neuroscience, 22(3), 1997, pp. 185-191

Abstract

Saturation binding of [H-3]paroxetine was performed in 10 brain regions from a group of suicide victims who had a firm, retrospective diagnosis of depression and who had been prescribed antidepressant drugs, as well as in a group of controls. The number of binding sites did not differ significantly between suicide victims and controls, apart from in putamen, where a lower number of sites was found in the suicide victims. Higher dissociation constant (K-d) values were found in suicide victims dying by antidepressant overdose and also in those dying by other means when compared with controls.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/01/20 alle ore 12:22:16