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Titolo:
Lipid metabolism, human evolution and schizophrenia
Autore:
Horrobin, DF;
Indirizzi:
Laxdale Res, Stirling FK7 9JQ, Scotland Laxdale Res Stirling Scotland FK7 9JQ le Res, Stirling FK7 9JQ, Scotland
Titolo Testata:
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
fascicolo: 5-6, volume: 60, anno: 1999,
pagine: 431 - 437
SICI:
0952-3278(199905/06)60:5-6<431:LMHEAS>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
FATTY-ACID-BINDING; LIPOPROTEIN-LIPASE GENE; RAT-BRAIN MICROSOMES; GROWTH INHIBITOR; MESSENGER-RNA; DEVELOPMENTAL REGULATION; ARACHIDONIC-ACID; MAMMARY-GLAND; SKIN-TYPE; B-FABP;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
55
Recensione:
Indirizzi per estratti:
Indirizzo: Horrobin, DF Laxdale Res, Kings Pk House,Laurelhill Business Pk, Stirling FK7 9JQ, Scotland Laxdale Res Kings Pk House,Laurelhill Business Pk Stirling Scotland FK7 9JQ
Citazione:
D.F. Horrobin, "Lipid metabolism, human evolution and schizophrenia", PROS LEUK E, 60(5-6), 1999, pp. 431-437

Abstract

There are only small genetic differences between humans and the great apes. Yet these differences must be very important. Major known differences include the accumulation of subcutaneous fat, the expansion of breasts and buttocks, the growth of the brain and the connectivity of neurons. All these involve lipid metabolism yet, because fat leaves no fossils, lipids are rarely mentioned in discussions of human evolution. This paper attempts to identify some candidate areas of lipid metabolism which may be important in human evolution. It draws attention to abnormalities in phospholipid metabolism in schizophrenia and suggests that these may have proved important in enhancing brain connectivity in the later stages of evolution of modern humans.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 20:50:40