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Titolo:
Reduced heart rate variability in patients affected with Rett syndrome. A possible explanation for sudden death
Autore:
Guideri, F; Acampa, M; Hayek, C; Zappella, N; Di Perri, T;
Indirizzi:
Univ Siena, Dept Child Neurol & Psychiat, I-53100 Siena, Italy Univ SienaSiena Italy I-53100 d Neurol & Psychiat, I-53100 Siena, Italy Univ Siena, Sch Med, Inst Clin Med, I-53100 Siena, Italy Univ Siena Siena Italy I-53100 Med, Inst Clin Med, I-53100 Siena, Italy
Titolo Testata:
NEUROPEDIATRICS
fascicolo: 3, volume: 30, anno: 1999,
pagine: 146 - 148
SICI:
0174-304X(199906)30:3<146:RHRVIP>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Keywords:
Rett syndrome; heart rate variability; sudden death; QTc;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Guideri, F Policlin Le Scotte, Ist Clin Med Gen & Terapia Med, Voale Bracci, I-53100 Siena, Italy Policlin Le Scotte Voale Bracci Siena Italy I-53100 ena, Italy
Citazione:
F. Guideri et al., "Reduced heart rate variability in patients affected with Rett syndrome. A possible explanation for sudden death", NEUROPEDIAT, 30(3), 1999, pp. 146-148

Abstract

Incidence of sudden death in Rett syndrome is greater than that of the general population and cardiac electrical instability is a prime suspect cause. Our study shows that girls with Rett syndrome had significantly lower heart rate variability (marker of autonomic disarray) and longer corrected QT intervals compared with an age-matched group of healthy girls. These abnormalities increased with advancing stages of the syndrome. These findings suggest a possible role of cardiac dysfunction in the sudden death associated with Rett syndrome.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 20:46:38