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Titolo:
Mycosis fungoides in patients under 20 years of age: Report of 7 cases, review of the literature and study of the clinical course
Autore:
Quaglino, P; Zaccagna, A; Verrone, A; Dardano, F; Bernengo, MG;
Indirizzi:
Univ Turin, Dermatol Sect, Dept Med & Surg Specialties, I-10126 Turin, Italy Univ Turin Turin Italy I-10126 & Surg Specialties, I-10126 Turin, Italy
Titolo Testata:
DERMATOLOGY
fascicolo: 1, volume: 199, anno: 1999,
pagine: 8 - 14
SICI:
1018-8665(1999)199:1<8:MFIPU2>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
T-CELL LYMPHOMA; SEZARY-SYNDROME; HTLV-I; CHILDHOOD; CHILDREN; RETROVIRUSES; DISEASE; GIRL; PUVA;
Keywords:
adolescence; age factors; childhood; immunophenotyping; mycosis fungoides; mycosis fungoides prognosis; mycosis fungoides survival;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Bernengo, MG Univ Turin, Dermatol Sect, Dept Med & Surg Specialties, Via Cherasco 23, I-10126 Turin, Italy Univ Turin Via Cherasco 23 Turin Italy I-10126 Turin, Italy
Citazione:
P. Quaglino et al., "Mycosis fungoides in patients under 20 years of age: Report of 7 cases, review of the literature and study of the clinical course", DERMATOLOGY, 199(1), 1999, pp. 8-14

Abstract

Background: Mycosis fungoides (MF) is rare in young patients. Its clinicalbehavior is still uncertain, as some reports have suggested that it has a more aggressive course than does the adult-onset type. Aim: To ascertain ifearly-onset MF represents a heterogeneous group of cutaneous T cell lymphomas. Materials and Methods: Clinical, immunohistopathological and follow-updata of early-onset (<20 years of age) MF cases reported in the literature(n = 42) plus 7 described herein were compared with those of a cohort of adult-onset MF patients (n = 252) diagnosed at our institution since 1975. Results: The majority of the 49 early-onset MF patients had patch-plaque stage disease at diagnosis, Ten had hypopigmented lesions. The predominant phenotype was CD3+ CD4+CD7-CD8-, Seven patients had a stage progression, 6 with extracutaneous involvement. Five- and 10-year survival rates were 93 and 74%, respectively, Conclusions: No statistically significant differences were found in the disease course between early- and adult-onset MF.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 15:31:28