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Titolo:
Anisotropy of water diffusion in corona radiata and cerebral peduncle in patients with hemiparesis
Autore:
Wieshmann, UC; Clark, CA; Symms, MR; Franconi, F; Barker, GJ; Shorvon, SD;
Indirizzi:
Univ Coll London, NSE Epilepsy Res MRI Unit, Epilepsy Res Grp, London WC1N3BG, England Univ Coll London London England WC1N 3BG es Grp, London WC1N3BG, England Univ Coll London, Inst Neurol, NMR Res Grp, Dept Clin Neurol, London WC1N 3BG, England Univ Coll London London England WC1N 3BG eurol, London WC1N 3BG, England
Titolo Testata:
NEUROIMAGE
fascicolo: 2, volume: 10, anno: 1999,
pagine: 225 - 230
SICI:
1053-8119(199908)10:2<225:AOWDIC>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
MAGNETIC-RESONANCE; WALLERIAN DEGENERATION; SPIN-ECHO; STROKE; BRAIN; NMR; COEFFICIENTS; TENSOR;
Keywords:
diffusion tensor imaging; anisotropy; hemiparesis; magnetic resonance imaging;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Wieshmann, UC Univ Coll London, NSE Epilepsy Res MRI Unit, Epilepsy Res Grp, London WC1N3BG, England Univ Coll London London England WC1N 3BG WC1N3BG, England
Citazione:
U.C. Wieshmann et al., "Anisotropy of water diffusion in corona radiata and cerebral peduncle in patients with hemiparesis", NEUROIMAGE, 10(2), 1999, pp. 225-230

Abstract

Diffusion tensor imaging is a magnetic resonance method which provides quantitative measurements of the directionality (anisotropy) of diffusion. Anisotropy measurements can be used to obtain quantitative information about the microstructural integrity of white matter tracts. In intact tracts diffusion is restricted and directional because water molecules move predominantly longitudinally to tracts. The aim of this study was to measure the anisotropy of diffusion in patients with chronic hemiparesis. We measured in thecorona radiata and the cerebral peduncle in 10 patients with a chronic hemiparesis and supratentorial lesions and 10 control subjects in regions of interest. In all patients anisotropy was reduced in the coronal radiata contralateral to the hemiparesis by more than 3 SD compared to control subjects. In three patients, each of which had a severe hemiparesis, anisotropy in the cerebral peduncle was reduced by more than 3 SD compared to normal control subjects. Our findings suggest that reduced anisotropy is associated with chronic hemiparesis. (C) 1999 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 10:57:55