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Titolo:
EXTENSION OF FUNDAMENTAL STROKE RESEARCH INTO CLINICAL CARE
Autore:
PLUM F;
Indirizzi:
CORNELL UNIV,COLL MED,DEPT NEUROL & NEUROSCI,525 E 68TH ST NEW YORK NY 10021
Titolo Testata:
Clinical neuroscience
fascicolo: 4, volume: 4, anno: 1997,
pagine: 175 - 178
SICI:
1065-6766(1997)4:4<175:EOFSRI>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE ISCHEMIC STROKE; DRUGS; INFARCTION; THERAPY;
Keywords:
STROKE TREATMENT; EXCITATORY AMINO ACIDS; GLUTAMATE BLOCKING AGENTS; CALCIUM CHANNEL BLOCKERS; ANTICOAGULANTS; THROMBOLYTIC AGENTS; STREPTOKINASE; RTPA; CRANIECTOMY FOR SEVERE STROKE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
F. Plum, "EXTENSION OF FUNDAMENTAL STROKE RESEARCH INTO CLINICAL CARE", Clinical neuroscience, 4(4), 1997, pp. 175-178

Abstract

Clinical efforts in stroke prevention have measurably reduced the incidence of stroke in persons experiencing a number of risk factors. Clinical efforts to reduce stroke size once the process starts, however, have been disappointing. A variety of agents aimed at blocking the effects of excitotoxic neurotransmitters or interfering with intracellular calcium entry have been tested but with little success on clinical outcome. Satisfactory explanation of the paradox between animal and clinical outcome studies has not been forthcoming. Accordingly, clinical investigators are exploring the potential value of surgical craniectomy in efforts to improve the presently devastated outcome that marks the course of severe, large acute cerebral infarctions. (C) 1997 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 01:35:31