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Titolo:
(R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionamides are orally active inhibitors of pyruvate dehydrogenase kinase
Autore:
Aicher, TD; Anderson, RC; Bebernitz, GR; Coppola, GM; Jewell, CF; Knorr, DC; Liu, C; Sperbeck, DM; Brand, LJ; Strohschein, RJ; Gao, JP; Vinluan, CC; Shetty, SS; Dragland, C; Kaplan, EL; DelGrande, D; Islam, A; Liu, XL; Lozito, RJ; Maniara, WM; Walter, RE; Mann, WR;
Indirizzi:
Novartis Inst Biomed Res, Chem Unit, Summit, NJ 07901 USA Novartis Inst Biomed Res Summit NJ USA 07901 m Unit, Summit, NJ 07901 USA Novartis Inst Biomed Res, Pharmacol Unit, Summit, NJ 07901 USA Novartis Inst Biomed Res Summit NJ USA 07901 l Unit, Summit, NJ 07901 USA Novartis Inst Biomed Res, DMPK Biotransformat, Summit, NJ 07901 USA Novartis Inst Biomed Res Summit NJ USA 07901 format, Summit, NJ 07901 USA Novartis Inst Biomed Res, Mol & Cellular Biol Unit, Summit, NJ 07901 USA Novartis Inst Biomed Res Summit NJ USA 07901 l Unit, Summit, NJ 07901 USA
Titolo Testata:
JOURNAL OF MEDICINAL CHEMISTRY
fascicolo: 15, volume: 42, anno: 1999,
pagine: 2741 - 2746
SICI:
0022-2623(19990729)42:15<2741:(AOAI>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEPENDENT DIABETES-MELLITUS; SODIUM DICHLOROACETATE; GLUCOSE-OXIDATION; SECONDARY-AMINES; MECHANISM; COMPLEX; PHOSPHORYLATION; HEART; RATS; ACID;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: Aicher, TD Novartis Inst Biomed Res, Chem Unit, 556 Morris Ave, Summit, NJ07901 USA Novartis Inst Biomed Res 556 Morris Ave Summit NJ USA 07901 USA
Citazione:
T.D. Aicher et al., "(R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionamides are orally active inhibitors of pyruvate dehydrogenase kinase", J MED CHEM, 42(15), 1999, pp. 2741-2746


ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/10/20 alle ore 20:28:44