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Titolo:
Mental stress test is an effective inducer of vasospastic angina pectoris:comparison with cold pressor, hyperventilation and master two-step exercise test
Autore:
Yoshida, K; Utsunomiya, T; Morooka, T; Yazawa, M; Kido, K; Ogawa, T; Ryu, T; Ogata, T; Tsuji, S; Tokushima, T; Matsuo, S;
Indirizzi:
Saga Med Sch, Dept Internal Med, Div Cardiol, Saga, Japan Saga Med Sch Saga Japan ch, Dept Internal Med, Div Cardiol, Saga, Japan
Titolo Testata:
INTERNATIONAL JOURNAL OF CARDIOLOGY
fascicolo: 2, volume: 70, anno: 1999,
pagine: 155 - 163
SICI:
0167-5273(19990731)70:2<155:MSTIAE>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; SILENT-MYOCARDIAL-ISCHEMIA; VARIANT ANGINA; DAILY-LIFE; REST; FREQUENCY;
Keywords:
mental calculation stress; vasospastic angina pectoris; hyperventilation test; cold pressor test; exercise test;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Yoshida, K Saga Med Sch, Dept Internal Med, Div Cardiol, Saga, Japan Saga Med Sch Saga Japan ternal Med, Div Cardiol, Saga, Japan
Citazione:
K. Yoshida et al., "Mental stress test is an effective inducer of vasospastic angina pectoris:comparison with cold pressor, hyperventilation and master two-step exercise test", INT J CARD, 70(2), 1999, pp. 155-163

Abstract

Background: Cold presser, hyperventilation and exercise stress tests were usually used for inducing an angina attack in patients with vasospastic angina pectoris. We induced vasospastic angina attack using the mental calculation stress test, and compared the results with those using other stress tests. Subjects and methods: Subjects were 29 patients with vasospastic angina pectoris. Their ages were 60.8+/-8.4 years. Coronary vasospasm was induced by an acetylcholine infusion test during coronary angiography. The mentalstress test was performed as follows; after memorizing six digits numbers,they repeated these numbers in reverse for 5 min, and performed serial subtraction of 17 from 1000 for 5 min. Blood pressure, heart rate and ECG wererecorded every 1-5 min during the mental stress test. The serum concentrations of epinephrine and norepinephrine were measured before and during the mental stress test. We compared these results with those obtained using cold presser, hyperventilation and the Master two-step exercise stress test. Results: (1) Eight of the 29 patients (28%) showed ischemic ST-T change, which was caused by the mental stress test. (2) The increase in norepinephrinewas greater in patients with an ST-T change than without an ST-T change (0.11+/-0.06 vs. 0.04+/-0.04 ng/ml, P<0.01). (3) The incidence of the ST-T change caused by the mental stress test (28%) was similar to the cold pressertest (27%) and greater than that caused by the hyperventilation test (13%). The incidence of ST-T change caused by the Master two-step test was 55%. Conclusions: The mental stress test is an effective inducer of vasospastic angina attack, and attack may be induced by neurohumoral vasoconstrictive reflex and/or increased left ventricular afterload. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 13:27:20