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Titolo:
In vitro and in vivo assessment of bone-implant interface: a comparative study
Autore:
De Benedittis, A; Mattioli-Belmonte, M; Krajewski, A; Fini, M; Ravaglioli, A; Giardino, R; Biagini, G;
Indirizzi:
Univ Ancona, Sch Med, CIBAD Ctr Innovat Biomat, I-60020 Ancona, Italy UnivAncona Ancona Italy I-60020 r Innovat Biomat, I-60020 Ancona, Italy Italian Natl Res Council, Inst Technol Res Ceram, Faenza, Italy Italian Natl Res Council Faenza Italy Technol Res Ceram, Faenza, Italy Univ Bologna, Rizzoli Orthopaed Inst, Res Inst Codivilla Putti, Dept Expt Surg, Bologna, Italy Univ Bologna Bologna Italy ivilla Putti, Dept Expt Surg, Bologna, Italy
Titolo Testata:
INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
fascicolo: 7, volume: 22, anno: 1999,
pagine: 516 - 521
SICI:
0391-3988(199907)22:7<516:IVAIVA>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
BIOACTIVE GLASS; STAINLESS-STEEL; OSTEOBLASTS;
Keywords:
biological glass; ceramic; implant coatings; osteoporosis; microanalysis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Mattioli-Belmonte, M Univ Ancona, Sch Med, CIBAD Ctr Innovat Biomat, Via Tronto 10-A, I-60020 Ancona, Italy Univ Ancona Via Tronto 10-A Ancona ItalyI-60020 aly
Citazione:
A. De Benedittis et al., "In vitro and in vivo assessment of bone-implant interface: a comparative study", INT J ARTIF, 22(7), 1999, pp. 516-521

Abstract

The present in vitro and in vivo comparison of three bioactive (HA, AP40, RKKP) and three bioinert (Ti6-Al4-V, Al2O3, ZrO2) materials was undertaken to identify which of them provide(s) the most suitable coating for prostheses implanted in patients with altered metabolic status. The experimental design included in vitro tests with human osteoblasts andmorphological observations by scanning electron microscopy. For the in vivo evaluation, the materials were implanted in the femoral condyle of ovariectomised and intact female rats, and two months after surgery an X-ray microanalytical study was performed. The in vitro study showed good biocompatibility with all materials. Microanalysis evidenced a similar behaviour with all materials except the two biological glasses. The differences in Ga and P content observed between intact and ovariectomised rats can be explained by the intrinsic capability of biological glasses to undergo surface modifications in the presence of alterations of the bone metabolism. Thus, their use seems to be indicated in recipients with osteoporotic pathologies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 05:26:48