Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Aspiration of dead space allows normocapnic ventilation at low tidal volumes in man
Autore:
De Robertis, E; Servillo, G; Jonson, B; Tufano, R;
Indirizzi:
Univ Lund Hosp, Dept Clin Physiol, S-22185 Lund, Sweden Univ Lund Hosp Lund Sweden S-22185 pt Clin Physiol, S-22185 Lund, Sweden Univ Naples Federico II, Dept Anaesthesia & Intens Care, Naples, Italy Univ Naples Federico II Naples Italy hesia & Intens Care, Naples, Italy
Titolo Testata:
INTENSIVE CARE MEDICINE
fascicolo: 7, volume: 25, anno: 1999,
pagine: 674 - 679
SICI:
0342-4642(199907)25:7<674:AODSAN>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRACHEAL GAS INSUFFLATION; SINGLE BREATH TEST; CARBON-DIOXIDE; MECHANICAL VENTILATION; CO2 REMOVAL; PRESSURE; ELIMINATION; DEADSPACE; CATHETER; DOGS;
Keywords:
mechanical ventilation; dead space; airway pressure; barotrauma; tracheal gas insufflation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Jonson, B Univ Lund Hosp, Dept Clin Physiol, S-22185 Lund, Sweden Univ Lund Hosp Lund Sweden S-22185 ysiol, S-22185 Lund, Sweden
Citazione:
E. De Robertis et al., "Aspiration of dead space allows normocapnic ventilation at low tidal volumes in man", INTEN CAR M, 25(7), 1999, pp. 674-679

Abstract

Objective: Aspiration of dead space (ASPIDS) improves carbon dioxide (CO2)elimination by replacing dead space air rich in CO2 with fresh gas during expiration. The hypothesis was that ASPIDS allows normocapnia to be maintained at low tidal volumes (V-T). Design: Prospective study. Setting: Adult intensive care unit in a university hospital. Patients: Seven patients ventilated for neurological reasons were studied. All patients were clinically and haemodynamically stable and monitored according to clinical needs. Interventions: ASPIDS implies that, during expiration, gas is aspirated through a catheter inserted in the tracheal tube. Simultaneously, a compensatory now of fresh gas is injected into the inspiratory line. ASPIDS was achieved with a computer/ventilator system controlling two solenoid valves for aspiration and injection. Results: At the basal respiratory rate of 12.6 breaths min(-1), with ASPIDS V-T decreased from 602 to 456 ml, as did the airway pressures to a corresponding degree. PaCO2 and PaO2 remained stable. At a frequency of 20 breaths min(-1), with ASPIDS V-T was further reduced to 305 mi with preserved normocapnia. ASPIDS did not interfere with the positive end-expiratory pressure (PEEP) level. No intrinsic PEEP developed. All patients remained stable. No haemodynamic or other side effects of ASPIDS were noticed. Conclusion: The results of this study suggest that ASPIDS may be a useful and safe modality of mechanical ventilation that limits alveolar pressure and minute ventilation requirements while keeping PaCO2 constant.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/09/20 alle ore 09:41:37