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Titolo:
Immune thrombocytopenia after umbilical cord progenitor cell transplant: response to vincristine
Autore:
Dovat, S; Roberts, RL; Wakim, M; Stiehm, ER; Feig, SA;
Indirizzi:
Univ Calif Los Angeles, Sch Med,UCLA Childrens Hosp, Dept Pediat, Div Hematol Oncol, Los Angeles, CA 90095 USA Univ Calif Los Angeles Los Angeles CAUSA 90095 Los Angeles, CA 90095 USA Univ Calif Los Angeles, Sch Med,UCLA Childrens Hosp, Dept Pediat, Div Immunol, Los Angeles, CA 90095 USA Univ Calif Los Angeles Los Angeles CA USA 90095 Los Angeles, CA 90095 USA
Titolo Testata:
BONE MARROW TRANSPLANTATION
fascicolo: 3, volume: 24, anno: 1999,
pagine: 321 - 323
SICI:
0268-3369(199908)24:3<321:ITAUCP>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
BONE-MARROW TRANSPLANTATION; SLOW INFUSION; HOST DISEASE; PURPURA;
Keywords:
immune thrombocytopenia; umbilical cord progenitor cell transplantation; vincristine; chronic graft-versus-host disease;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Dovat, S Univ Calif Los Angeles, Sch Med,UCLA Childrens Hosp, Dept Pediat,Div Hematol Oncol, 10833 Le Conte Ave, Los Angeles, CA 90095 USA Univ Calif Los Angeles 10833 Le Conte Ave Los Angeles CA USA 90095
Citazione:
S. Dovat et al., "Immune thrombocytopenia after umbilical cord progenitor cell transplant: response to vincristine", BONE MAR TR, 24(3), 1999, pp. 321-323

Abstract

An 8-month-old male with X-linked lymphoproliferative disease underwent anunrelated, partially matched (with major mismatch at DR locus), cord bloodstem cell transplant. Four months following the transplant, he developed immune thrombocytopenia with hemolytic anemia (Evans syndrome). He received multiple courses of intravenous immunoglobulin, anti-Rh D immunoglobulin, apulse of high-dose corticosteroids and cyclosporine with some improvement of hemolytic anemia, but no improvement of the thrombocytopenia, Addition of vincristine, resulted in long-term resolution of thrombocytopenia and anemia, No major toxicity was observed during treatment. Vincristine should beconsidered as a treatment for refractory immune thrombocytopenia after hematopoietic stem cell transplantation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 00:46:26