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Titolo:
The spiroketals containing a benzyloxymethyl moiety at C8 position showed the most potent apoptosis-inducing activity.
Autore:
Mitsuhashi, S; Shima, H; Kawamura, T; Kikuchi, K; Oikawa, M; Ichihara, A; Oikawa, H;
Indirizzi:
Hokkaido Univ, Inst Immunol Sci, Biochem Sect, Kita Ku, Sapporo, Hokkaido 0600815, Japan Hokkaido Univ Sapporo Hokkaido Japan 0600815 oro, Hokkaido 0600815, Japan Hokkaido Univ, Fac Agr, Dept Biosci & Chem, Kita Ku, Sapporo, Hokkaido 0608589, Japan Hokkaido Univ Sapporo Hokkaido Japan 0608589 oro, Hokkaido 0608589, Japan
Titolo Testata:
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
fascicolo: 14, volume: 9, anno: 1999,
pagine: 2007 - 2012
SICI:
0960-894X(19990719)9:14<2007:TSCABM>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
TAUTOMYCIN; INHIBITION; INDUCTION; PROTEIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
8
Recensione:
Indirizzi per estratti:
Indirizzo: Kikuchi, K Hokkaido Univ, Inst Immunol Sci, Biochem Sect, Kita Ku, Kita 15,Nishi 7, Sapporo, Hokkaido 0600815, Japan Hokkaido Univ Kita 15,Nishi 7 Sapporo Hokkaido Japan 0600815 an
Citazione:
S. Mitsuhashi et al., "The spiroketals containing a benzyloxymethyl moiety at C8 position showed the most potent apoptosis-inducing activity.", BIOORG MED, 9(14), 1999, pp. 2007-2012

Abstract

The spiroketals containing a benzyloxymethyl moiety at the C8 position showed the most potent apoptosis-inducing activity, whereas its analogous compounds lacking any substituent at C8 or possessing ones other than the benzyloxymethyl moiety at C8 were all much less active, These results strongly suggest an important role of the benzyloxymethyl moiety linked to the C8 oxygen atom. (C) 1999 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 06:07:14