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Titolo:
Rotavirus infection associated with adult thrombotic microangiopathy
Autore:
Klisnick, A; Soriano, C; Gazuy, N; Forestier, C; Peigue-Lafeuille, H;
Indirizzi:
CHU, Serv Reanimat Med Polyvalente, Clermont Ferrand, France CHU ClermontFerrand France t Med Polyvalente, Clermont Ferrand, France CHU, Bacteriol Lab, Clermont Ferrand, France CHU Clermont Ferrand France HU, Bacteriol Lab, Clermont Ferrand, France CHU, Virol Lab, Clermont Ferrand, France CHU Clermont Ferrand FranceCHU, Virol Lab, Clermont Ferrand, France
Titolo Testata:
PRESSE MEDICALE
fascicolo: 24, volume: 28, anno: 1999,
pagine: 1287 - 1289
SICI:
0755-4982(19990703)28:24<1287:RIAWAT>2.0.ZU;2-E
Fonte:
ISI
Lingua:
FRE
Soggetto:
HEMOLYTIC-UREMIC SYNDROME; ESCHERICHIA-COLI; TOXIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Klisnick, A CHG, Serv Med Interne, 10 Ave Gen de Gaulle,BP 609, F-03006 Moulins, France CHG 10 Ave Gen de Gaulle,BP 609 Moulins France F-03006 France
Citazione:
A. Klisnick et al., "Rotavirus infection associated with adult thrombotic microangiopathy", PRESSE MED, 28(24), 1999, pp. 1287-1289

Abstract

BACKGROUND: A preceding viral syndrome is classically cited as a triggering factor for thrombotic micorangiopathy although only anecdotal reports of the causal agent have been documented. CASE REPORT: An 84-year-old woman developed thrombotic microangiopathy secondary to diarrhea. An exhaustive etiological work-up documented the presence of Rotavirus alone in the fecal matter. The clinical course was favorable after 9 plasma exchanges, using frozen fresh plasma and was associated with disappearance of the Rotavirus. DISCUSSION: Enterohemorrhagic Escherichia coli is the most commonly identified infectious agent causing thrombotic microangiopathy. A small number ofcases caused by viral agents (particularly retroviruses) have also been documented. To our knowledge, this is the first case attributable to a Rotavirus. In our case, the presence of the Rotavirus in the fecal matter and thefavorable clinical course when the virus disappeared would be in favor of its causal role in the pathogenesis of thrombotic micorangiopathy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 15:27:03