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Titolo:
Risperidone treatment for juvenile bipolar disorder: A retrospective chartreview
Autore:
Frazier, JA; Meyer, MC; Biederman, J; Wozniak, J; Wilens, TE; Spencer, TJ; Kim, GS; Shapiro, S;
Indirizzi:
Harvard Univ, Sch Med, Massachusetts Gen Hosp, Child Psychiat Dept, Boston, MA 02114 USA Harvard Univ Boston MA USA 02114 hild Psychiat Dept, Boston, MA 02114 USA
Titolo Testata:
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
fascicolo: 8, volume: 38, anno: 1999,
pagine: 960 - 965
SICI:
0890-8567(199908)38:8<960:RTFJBD>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEFICIT HYPERACTIVITY DISORDER; MANIA; CHILDREN; ADOLESCENTS; SCHIZOPHRENIA; COMORBIDITY; DYSKINESIA; TARDIVE; AUTISM;
Keywords:
juvenile; bipolar disorder; risperidone;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Frazier, JA Harvard Univ, Sch Med, Massachusetts Gen Hosp, Child Psychiat Dept, ACC 725,15 Parkman St, Boston, MA 02114 USA Harvard Univ ACC 725,15 Parkman St Boston MA USA 02114 114 USA
Citazione:
J.A. Frazier et al., "Risperidone treatment for juvenile bipolar disorder: A retrospective chartreview", J AM A CHIL, 38(8), 1999, pp. 960-965

Abstract

Objective: To investigate the effectiveness and tolerability of the atypical neuroleptic risperidone in the treatment of juvenile mania. Method: Thisis a retrospective chart review of outpatients with the diagnosis of bipolar disorder (DSM-IV) treated with risperidone at a university center. Response to treatment was evaluated using the Clinical Global Impression Scale (CGI) with separate assessments of mania, psychosis, aggression, and attention-deficit/hyperactivity disorder (ADHD). Results: Twenty-eight youths (mean +/- SD age, 10.4 +/- 3.8 years) with bipolar disorder (25 mixed and 3 hypomanic) who had been treated with risperidone were identified. These children received a mean dose of 1.7 +/- 1.3 mg over an average period of 6.1 +/-8.5 months. Using a CGI Improvement score of less than or equal to 2 (verymuch/much improved) to define robust improvement, 82% showed improvement in both their manic and aggressive symptoms, 69% in psychotic symptoms, but only 8% in ADHD symptoms. Conclusions: Although limited by its retrospective nature, this study suggests that risperidone may be effective in the treatment of manic young people and indicates the need for controlled clinical trials of risperidone and other atypical neuroleptics in juvenile mania.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 07:42:19