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Titolo:
Experimental inoculation of conventional pigs with tissue homogenates frompigs with post-weaning multisystemic wasting syndrome
Autore:
Balasch, M; Segales, J; Rosell, C; Domingo, M; Mankertz, A; Urniza, A; Plana-Duran, J;
Indirizzi:
Ft Dodge Vet, Vall de Bianya 17813, Spain Ft Dodge Vet Vall de Bianya Spain 17813 Vet, Vall de Bianya 17813, Spain Univ Autonoma Barcelona, Fac Vet, Bellaterra 08193, Spain Univ Autonoma Barcelona Bellaterra Spain 08193 , Bellaterra 08193, Spain Robert Koch Inst, D-13353 Berlin, Germany Robert Koch Inst Berlin Germany D-13353 ch Inst, D-13353 Berlin, Germany
Titolo Testata:
JOURNAL OF COMPARATIVE PATHOLOGY
fascicolo: 2, volume: 121, anno: 1999,
pagine: 139 - 148
SICI:
0021-9975(199908)121:2<139:EIOCPW>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
PORCINE CIRCOVIRUS; DISEASE; SPAIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Balasch, M Ft Dodge Vet, Carretera Camprodon S-N, Vall de Bianya 17813, Spain Ft Dodge Vet Carretera Camprodon S-N Vall de Bianya Spain 17813
Citazione:
M. Balasch et al., "Experimental inoculation of conventional pigs with tissue homogenates frompigs with post-weaning multisystemic wasting syndrome", J COMP PATH, 121(2), 1999, pp. 139-148

Abstract

This report describes the experimental inoculation of conventional pigs with a tissue homogenate obtained from two pigs affected with postweaning multisystemic wasting syndrome (PMWS). Eight 2-month-old pigs were inoculated by the intranasal route, and two pigs were left as uninfected controls. Clinical signs, rectal temperatures and body weights were recorded. Pigs were necropsied at days 14 or 21 post-inoculation, and tissue samples were takenfor histopathology and porcine circovirus (PCV) in-situ hybridization. Although only mild clinical signs of disease were observed, lesions of PMWS were seen, and PCV was shown to have been successfully transmitted to six of the eight pigs. Seroconversion of all inoculated pigs to PCV-2, but not to PCV-1, was also detected, suggesting that the PCV nucleic acid detected by in-situ hybridization in inoculated pigs corresponded to PCV-2. In conclusion. this report shows that PCV-2 is transmissible to pigs, and the inoculation of tissue homogenates containing the virus results in the development of PMWS-like lesions. (C) 1999 W.B. Saunders Company Limited.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 03:33:15