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Titolo:
Cow's milk casein, a hidden allergen in natural rubber latex gloves
Autore:
Ylitalo, L; Makinen-Kiljunen, S; Turjanmaa, K; Palosuo, T; Reunala, T;
Indirizzi:
Tampere Univ Hosp, Dept Dermatol, FIN-33521 Tampere, Finland Tampere Univ Hosp Tampere Finland FIN-33521 , FIN-33521 Tampere, Finland Univ Helsinki, Cent Hosp, Hosp Skin & Allerg Dis, Helsinki, Finland Univ Helsinki Helsinki Finland osp Skin & Allerg Dis, Helsinki, Finland Natl Publ Hlth Inst, Helsinki, Finland Natl Publ Hlth Inst Helsinki Finland Publ Hlth Inst, Helsinki, Finland Univ Tampere, Sch Med, Tampere, Finland Univ Tampere Tampere FinlandUniv Tampere, Sch Med, Tampere, Finland
Titolo Testata:
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
fascicolo: 1, volume: 104, anno: 1999,
pagine: 177 - 180
SICI:
0091-6749(199907)104:1<177:CMCAHA>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
SKIN PRICK TEST; MEDICAL GLOVES; FOOD ALLERGY; CHILDREN; INFANTS;
Keywords:
latex gloves; cow's milk allergy; casein; latex allergy testing;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Ylitalo, L Tampere Univ Hosp, Dept Dermatol, POB 2000, FIN-33521 Tampere, Finland Tampere Univ Hosp POB 2000 Tampere Finland FIN-33521 , Finland
Citazione:
L. Ylitalo et al., "Cow's milk casein, a hidden allergen in natural rubber latex gloves", J ALLERG CL, 104(1), 1999, pp. 177-180

Abstract

Background: We have previously noted that one natural rubber latex (NRL) glove brand used for skin prick testing in the diagnosis of NRL allergy contained cow's milk casein. Objective: We sought to examine whether other commonly marketed NRL glove brands contain cow's milk casein,Methods: The casein content of 30 NRL glove extracts (1:5 wt/vol) was measured by RAST inhibition and by rocket immunoelectrophoresis and rocket radioimmunoelectrophoresis by using casein-specific rabbit antiserum, a serum pool from patients with cow's milk allergy, and radiolabeled antihuman IgE, The NRL allergen content was measured by ELISA inhibition. Results: The casein content of the glove used in NRL allergy screening (Triflex, Baxter) was rather high (ie, about 400 mu g/g of glove). Its total protein content was 1000 mu g/g of glove. Rocket radioimmunoelectrophoresis detected distinct amounts of casein in 8, minimal amounts in 7, and no casein in the remaining 15 NRL glove brands. Conclusions: Several brands of NRL gloves were found to contain casein, implying that extracts prepared from such gloves can cause false-positive skin prick test reactions when diagnosing NRL allergy. The use of casein as a stabilizer in glove manufacture without appropriate labeling should be stopped because it can also cause contact urticaria syndrome in individuals with cow's milk allergy.

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Documento generato il 23/01/21 alle ore 07:48:26