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Titolo:
Deletion polymorphism in the gene for angiotensin-converting enzyme is nota risk factor predisposing to abdominal aortic aneurysm
Autore:
Hamano, K; Ohishi, M; Ueda, M; Fujioka, K; Katoh, T; Zempo, N; Fujimura, Y; Okamura, A; Rakugi, H; Higaki, J; Ogihara, T; Esato, K;
Indirizzi:
Yamaguchi Univ, Sch Med, Dept Surg 1, Yamaguchi 7558505, Japan Yamaguchi Univ Yamaguchi Japan 7558505 Surg 1, Yamaguchi 7558505, Japan
Titolo Testata:
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
fascicolo: 2, volume: 18, anno: 1999,
pagine: 158 - 161
SICI:
1078-5884(199908)18:2<158:DPITGF>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEFT-VENTRICULAR HYPERTROPHY; ISCHEMIC-HEART-DISEASE; MYOCARDIAL-INFARCTION; ASSOCIATION; EXPRESSION; ATHEROSCLEROSIS; GENOTYPE; LINKAGE; GROWTH; HUMANS;
Keywords:
abdominal aortic aneurysm; angiotensin converting enzyme; polymorphism; gene;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Hamano, K Yamaguchi Univ, Sch Med, Dept Surg 1, Yamaguchi 7558505, Japan Yamaguchi Univ Yamaguchi Japan 7558505 amaguchi 7558505, Japan
Citazione:
K. Hamano et al., "Deletion polymorphism in the gene for angiotensin-converting enzyme is nota risk factor predisposing to abdominal aortic aneurysm", EUR J VAS E, 18(2), 1999, pp. 158-161

Abstract

Objective: to establish whether deletion of the angiotensin-converting enzyme (ACE) Seize is a risk factor predisposing to abdominal aortic aneurysm (AAA) or nor. Methods: the study included 125 patients with AAA and 153 controls randomly selected from 328 individuals. The control subjects were confirmed not tohave an AAA, but matched with the AAA group for age, sex, hypertension, diabetes mellitus, and hyperlipidaemia. The presence of ACE polymorphism was detected by a polymerase chain reaction using DNA extracted from blood. Results: the distribution of ACE genotypes and allele frequencies in the control and AAA groups was not significantly different. Conclusion: the deletion polymorphism in the ACE gene is not a risk factorfor AAA.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 00:59:21