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Titolo:
Predictors of stent thrombosis after primary stenting for acute myocardialinfarction
Autore:
Silva, JA; Nunez, E; White, CJ; Collins, TJ; Jenkins, JS; Zhang, SY; Jain, SP; Ramee, SR;
Indirizzi:
Alton Ochsner Med Fdn & Ochsner Clin, Dept Cardiol, New Orleans, LA 70121 USA Alton Ochsner Med Fdn & Ochsner Clin New Orleans LA USA 70121 A 70121 USA
Titolo Testata:
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
fascicolo: 4, volume: 47, anno: 1999,
pagine: 415 - 422
SICI:
1522-1946(199908)47:4<415:POSTAP>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLASMINOGEN-ACTIVATOR INHIBITOR; DEPENDENT DIABETES-MELLITUS; TISSUE FACTOR EXPRESSION; HUMAN-ENDOTHELIAL-CELLS; PLATELET ACTIVATION; HEMOSTATIC FUNCTION; VASCULAR-DISEASE; ANTIPLATELET THERAPY; ULTRASOUND GUIDANCE; INSULIN SENSITIVITY;
Keywords:
ischemia; abrupt occlusion;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
63
Recensione:
Indirizzi per estratti:
Indirizzo: Ramee, SR Alton Ochsner Med Fdn & Ochsner Clin, Dept Cardiol, 1514 Jefferson Highway, New Orleans, LA 70121 USA Alton Ochsner Med Fdn & Ochsner Clin 1514 Jefferson Highway New Orleans LA USA 70121
Citazione:
J.A. Silva et al., "Predictors of stent thrombosis after primary stenting for acute myocardialinfarction", CATHET C IN, 47(4), 1999, pp. 415-422

Abstract

The aim of the study was to determine if a hypercoagulable state that may persist for several months after an acute myocardial infarction may contribute to an increased incidence of stent thrombosis. Primary stenting was performed in 104 consecutive patients with acute myocardial infarction using 147 coronary stents. Twenty-eight patients (27%) were diabetic and 55 patients (53%) were smokers. A single stent was placed in 63%, two stents in 33%,and more than two stents in 4% of the patients. Procedural success was obtained in 97% of the patients. All stents were deployed using high-pressure balloon inflation. The reference vessel diameter and minimal lumen diameterafter stent deployment were 3.30 +/- 0.42 and 3.23 +/- 0.42 mm, respectively. Six patients (5.7%) developed stent thrombosis within 1 month after theprocedure complicated by reinfarction in five of the six patients. At 1-month follow-up, all patients remained alive. On multivariate analysis, independent predictors of stent thrombosis were diabetes mellitus (relative risk[RR] 5.2; 95% confidence interval [CI] 1.8, 25.1), tobacco use (RR 4.5; 95% CI 1.3, 24.5), number of stents: 1 vs. > 1 (RR 3.7; 95% CI 1.1, 15.9), minimal lumen diameter poststent placement (RR 0.03; 95% CI 0.0002, 0.74), and duration of chest pain before intervention (RR 1.1; 95% CI 1.01, 1.25), Stent thrombosis had not been associated with diabetes mellitus and tobacco use previously but is in agreement with the enhanced platelet aggregability, coagulation factor abnormalities, and impaired fibrinolysis characteristic of these patients. Cathet Cardiovasc. Intervent. 47:415-422, 1999. (C) 1999 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 03:57:18