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Titolo:
Isolation and genetic characterization of a hantavirus (Bunyaviridae : Hantavirus) from a rodent, Oligoryzomys microtis (Muridae), collected in northeastern Peru
Autore:
Powers, AM; Mercer, DR; Watts, DM; Guzman, H; Fulhorst, CF; Popov, VL; Tesh, RB;
Indirizzi:
Univ Texas, Med Branch, Dept Pathol, Galveston, TX 77555 USA Univ Texas Galveston TX USA 77555 h, Dept Pathol, Galveston, TX 77555 USA USN, Med Res Inst Detachment, NAMRID, Unit 3800, APO, AA 34031 USA USN APO AA USA 34031 nst Detachment, NAMRID, Unit 3800, APO, AA 34031 USA
Titolo Testata:
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
fascicolo: 1, volume: 61, anno: 1999,
pagine: 92 - 98
SICI:
0002-9637(199907)61:1<92:IAGCOA>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
PULMONARY SYNDROME; FAMILY BUNYAVIRIDAE; SIGMODON HISPIDUS; VIRUS; ARGENTINA; IDENTIFICATION; EPIDEMIOLOGY; DIVERSITY; INFECTION; SEROTYPE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Tesh, RB Univ Texas, Med Branch, Dept Pathol, 301 Univ Blvd, Galveston, TX77555 USA Univ Texas 301 Univ Blvd Galveston TX USA 77555 ton, TX 77555 USA
Citazione:
A.M. Powers et al., "Isolation and genetic characterization of a hantavirus (Bunyaviridae : Hantavirus) from a rodent, Oligoryzomys microtis (Muridae), collected in northeastern Peru", AM J TROP M, 61(1), 1999, pp. 92-98

Abstract

This payer describes the isolation and partial genetic characterization ofa hantavirus front a pygmy rice rat, Oligoryzomys microtis, collected within the urban area of Iquitos, Loreto Department, Peru. The virus, designated HTN-007, exhibited the highest degree of genetic similarity to Rio Mamorevirus, which was originally described from the same rodent species in eastern Bolivia. Comparison of small and medium segment nucleotide sequence data from HTN-007 and Rio Mamore virus revealed 87% and 85% sequence identity,respectively. Based on these analyses, HTN-007 appears to be a variant of Rio Mamore virus. As such, it represents the first successful isolation of Rio Mamore virus and the first evidence for the existence of a hantavirus in Peru. Serologic studies done by immunofluorescence on blood samples of 56O. microtis trapped at the collection site indicated that 21.4% had antibodies to hantavirus. In view of the proximity of this rodent species to humans and the close phylogenetic relationship of Rio Mamore virus to hantaviruses that have been associated with human disease, Rio Mamore virus may be ahantavirus of some public health importance in tropical South America.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 08:19:40