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Titolo:
Impact of shift work on cardiovascular functions in a 10-year follow-up study
Autore:
Murata, K; Yano, E; Shinozaki, T;
Indirizzi:
Teikyo Univ, Sch Med, Dept Hyg & Publ Hlth, Itabashi Ku, Tokyo 1738605, Japan Teikyo Univ Tokyo Japan 1738605 Hlth, Itabashi Ku, Tokyo 1738605, Japan
Titolo Testata:
SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH
fascicolo: 3, volume: 25, anno: 1999,
pagine: 272 - 277
SICI:
0355-3140(199906)25:3<272:IOSWOC>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
QT INTERVAL PROLONGATION; ISCHEMIC-HEART-DISEASE; SUDDEN CARDIAC DEATH; MYOCARDIAL-INFARCTION; RATE-VARIABILITY; RISK; ENVIRONMENT; MORTALITY; OVERTIME;
Keywords:
blood pressure; cardiovascular effect; heart rate-adjusted QT interval; shift work;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Yano, E Teikyo Univ, Sch Med, Dept Hyg & Publ Hlth, Itabashi Ku, 2-11-1 Kaga, Tokyo 1738605, Japan Teikyo Univ 2-11-1 Kaga Tokyo Japan 1738605 Tokyo 1738605, Japan
Citazione:
K. Murata et al., "Impact of shift work on cardiovascular functions in a 10-year follow-up study", SC J WORK E, 25(3), 1999, pp. 272-277

Abstract

Objectives The purpose of this study was to determine whether shift work affects the heart-rate-adjusted QT interval (QTc) in electorcardiography (ECG) and the blood pressure of workers without overt cardiovascular dysfunction. Methods At a copper smelter, 158 shift workers and 75 day workers who underwent an ECG examination and blood pressure measurements in 1986 were followed for 10 years. In 1996, biochemical indicators such as high-density lipoprotein cholesterol and triglycerides were measured, together with the QTc. Results In 1986 and 1996, the QTc was significantly longer in the shift workers than in the day workers. Of 180 workers with a normal QTc (<420 ms(1/2)) in 1986, 15% had developed a prolonged QTc (420 ms(1/2)) in 1996 (18% of the 117 shift workers and 11% of the 63 day workers). Among the workers with a normal QTc in 1986, the shift workers had a significantly longer QTc than the day workers when the QTc was examined in 1996. In addition, shift-day work in the group with a normal QTc was significantly related to the QTc in 1996 after control for age, work duration, biochemical indicators, smoking, and drinking habits. However, the blood pressures of the shift and day workers did not differ significantly, and in 1996 the values of both groups were significantly elevated. Conclusions These data suggest that shift work is associated with QTc prolongation. This evidence may explain the increased risk for cardiovascular diseases due to shift work.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 03:11:58