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Titolo:
Mast cell sarcoma with tissue eosinophilia arising in the ascending colon
Autore:
Kojima, M; Nakamura, S; Itoh, H; Ohno, Y; Masawa, N; Joshita, T; Suchi, T;
Indirizzi:
Dokkyo Univ, Sch Med, Dept Pathol, Mibu, Tochigi 3210293, Japan Dokkyo Univ Mibu Tochigi Japan 3210293 thol, Mibu, Tochigi 3210293, Japan Aichi Canc Ctr Hosp, Nagoya, Aichi 464, Japan Aichi Canc Ctr Hosp Nagoya Aichi Japan 464 Hosp, Nagoya, Aichi 464, Japan Maebashi Red Cross Hosp, Maebashi, Gumma, Japan Maebashi Red Cross Hosp Maebashi Gumma Japan osp, Maebashi, Gumma, Japan Tone Cent Hosp, Dept Pathol, Numata, Japan Tone Cent Hosp Numata JapanTone Cent Hosp, Dept Pathol, Numata, Japan Gunma Univ, Sch Med, Dept Clin Labs, Maebashi, Gumma 371, Japan Gunma Univ Maebashi Gumma Japan 371 Clin Labs, Maebashi, Gumma 371, Japan
Titolo Testata:
MODERN PATHOLOGY
fascicolo: 7, volume: 12, anno: 1999,
pagine: 739 - 743
SICI:
0893-3952(199907)12:7<739:MCSWTE>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
GASTROINTESTINAL-TRACT; SYSTEMIC MASTOCYTOSIS; DISEASE; TRYPTASE; CHLOROMA;
Keywords:
ascending colon; eosinophils; mast cell sarcoma; mast cell tryptase;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Kojima, M Dokkyo Univ, Sch Med, Dept Pathol, Mibu, Tochigi 3210293, Japan Dokkyo Univ Mibu Tochigi Japan 3210293 , Tochigi 3210293, Japan
Citazione:
M. Kojima et al., "Mast cell sarcoma with tissue eosinophilia arising in the ascending colon", MOD PATHOL, 12(7), 1999, pp. 739-743

Abstract

Mast cell sarcoma is a rare disease. We report an unusual case of this neoplasm arising in the ascending colon of a 32-year-old Japanese woman who presented with abdominal pain. An ulcerating mass in the colon was resected, along with enlarged mesenteric lymph nodes. Two years after surgery, the neoplasm recurred as left cervical lymphadenopathy and an intra-abdominal mass, Despite predonine and radiation therapy, the disease progressed, and thepatient died. The tumor cells had abundant fine granular or clear cytoplasm, and oval, lobulated, or indented nuclei, Numerous mature eosinophils were intermingled with the tumor cells. Immunohistologic studies on paraffin sections demonstrated that the majority of the tumor cells were strongly positive for CD45RB, CD68, and mast cell tryptase. They were unreactive, however, with a broad spectrum of antibodies against myelomonocytic and lymphocytic antigens. The mast cell nature of this rare type of tumor can be best identifiable by immunostains for mast cell tryptase.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 05:23:03