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Titolo:
Magnetization transfer measurements in normal-appearing cerebral white matter in patients with chronic obstructive hydrocephalus
Autore:
Hahnel, S; Munkel, K; Jansen, O; Heiland, S; Reidel, M; Freund, M; Aschoff, A; Sartor, K;
Indirizzi:
Univ Heidelberg, Dept Neuroradiol, Sch Med, D-69120 Heidelberg, Germany Univ Heidelberg Heidelberg Germany D-69120 , D-69120 Heidelberg, Germany Univ Heidelberg, Sch Med, Dept Neurosurg, D-69120 Heidelberg, Germany UnivHeidelberg Heidelberg Germany D-69120 , D-69120 Heidelberg, Germany
Titolo Testata:
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY
fascicolo: 4, volume: 23, anno: 1999,
pagine: 516 - 520
SICI:
0363-8715(199907/08)23:4<516:MTMINC>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTIPLE-SCLEROSIS; MR; BRAIN; LESIONS; DISEASE; SYSTEM;
Keywords:
brain, white matter; brain, anatomy; magnetic resonance imaging; hydrocephalus; brain abnormalities;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Hahnel, S Univ Heidelberg, Dept Neuroradiol, Sch Med, Neuenheimer Feld 400, D-69120 Heidelberg, Germany Univ Heidelberg Neuenheimer Feld 400 Heidelberg Germany D-69120
Citazione:
S. Hahnel et al., "Magnetization transfer measurements in normal-appearing cerebral white matter in patients with chronic obstructive hydrocephalus", J COMPUT AS, 23(4), 1999, pp. 516-520

Abstract

Purpose: The purpose of this work was to assess the presence of subtle changes in normal-appearing white matter on T2-weighted MR images in patients with chronic obstructive hydrocephalus using magnetization transfer (MT) measurements. Method: In 12 patients with chronic obstructive hydrocephalus, MT ratios (MTRs) of normal-appearing rostral (PR) and caudal (PC) periventricular white matter, of the genu (CG) and the splenium (CS) of the corpus callosum, and of the thalamus (TH) were measured and compared with those of 16 healthy control subjects. Results: We found a significantly lower MTR in chronic obstructive hydrocephalus than in the normal group for PR, PC, CG, and CS but not for TH. Conclusion: Our study shows that MT measurements give additional information that cannot be gained by conventional SE MRI, suggesting that chronic obstructive hydrocephalus is associated with diffuse white matter damage thatalso affects normal-appearing cerebral white matter.

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Documento generato il 04/04/20 alle ore 15:24:22