Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Diffusion-weighted single-shot echoplanar MR imaging for liver disease
Autore:
Kim, T; Murakami, T; Takahashi, S; Hori, M; Tsuda, K; Nakamura, H;
Indirizzi:
Osaka Univ, Sch Med, Dept Radiol, Suita, Osaka 5650871, Japan Osaka Univ Suita Osaka Japan 5650871 Radiol, Suita, Osaka 5650871, Japan
Titolo Testata:
AMERICAN JOURNAL OF ROENTGENOLOGY
fascicolo: 2, volume: 173, anno: 1999,
pagine: 393 - 398
SICI:
0361-803X(199908)173:2<393:DSEMIF>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTRAVOXEL INCOHERENT MOTION; DYNAMIC BOLUS CT; HEPATOCELLULAR-CARCINOMA; HEPATIC HEMANGIOMA; PERFUSION; ENHANCEMENT; ANGIOGRAPHY; LESIONS; BENIGN; MASSES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Kim, T Osaka Univ, Sch Med, Dept Radiol, 2-2 Yamadaoka, Suita, Osaka 5650871, Japan Osaka Univ 2-2 Yamadaoka Suita Osaka Japan 5650871 a 5650871, Japan
Citazione:
T. Kim et al., "Diffusion-weighted single-shot echoplanar MR imaging for liver disease", AM J ROENTG, 173(2), 1999, pp. 393-398

Abstract

OBJECTIVE. The aims of this study were to determine apparent diffusion coefficients (ADCs) of the abdominal organs and liver lesions, to determine the effect of the magnitude of b values on the ADCs, and to determine whethermeasured ADCs of liver tumors help differentiate benign from malignant lesions. SUBJECTS AND METHODS. Six healthy volunteers and 126 patients were examined with diffusion-weighted single shot echoplanar imaging using multiple b values (maximum, 846 sec/mm(2)). The ADCs of the liver, spleen, kidney, 49 malignant liver lesions (33 hepatocellular carcinomas, 15 metastatic liver tumors, and one cholangiocellular carcinoma), and 30 benign lesions (17 cysts, 12 hemangiomas, and one angiomyolipoma) were calculated. RESULTS. The ADCs of the abdominal organs and liver lesions showed smallervalues when calculated with the greater maximum b values. The ADCs of the benign lesions calculated with all the b values of less than 850 sec/mm(2) (2.49 +/- 1.39 x 10(-3) mm(2)/sec) were significantly (p = .0024) greater than those of the malignant lesions (1.01 +/- 0.38 x 10(-3) mm(2)/sec). Whenthe maximum b value is 846 sec/mm(2), use of a threshold ADC of 1.6 x 10(-3) mm(2)/sec would result in a sensitivity of 98% and a specificity of 80% for differentiation of malignant liver lesions from benign lesions. CONCLUSION. Measurement of ADC has good potential for characterizing liverlesions, but the calculated ADCs could be affected by the magnitude of themaximum b value.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 16:43:16