Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Risk assessment of nephrotoxicity of cadmium
Autore:
Fels, LM;
Indirizzi:
Hannover Med Sch, Div Nephrol, D-30625 Hannover, Germany Hannover Med SchHannover Germany D-30625 rol, D-30625 Hannover, Germany
Titolo Testata:
RENAL FAILURE
fascicolo: 3-4, volume: 21, anno: 1999,
pagine: 275 - 281
SICI:
0886-022X(1999)21:3-4<275:RAONOC>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
RENAL-FUNCTION; EARLY MARKERS; HEAVY-METALS; WORKERS; EXPOSURE; METALLOTHIONEIN; HEPATOTOXICITY; INDICATORS; TOXICITY; KIDNEY;
Keywords:
nephrotoxicity; cadmium; biomarkers;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
45
Recensione:
Indirizzi per estratti:
Indirizzo: Fels, LM Hannover Med Sch, Div Nephrol, Carl Neuberg Str, D-30625 Hannover, Germany Hannover Med Sch Carl Neuberg Str Hannover Germany D-30625 rmany
Citazione:
L.M. Fels, "Risk assessment of nephrotoxicity of cadmium", RENAL FAIL, 21(3-4), 1999, pp. 275-281

Abstract

Cadmium as an environmental or occupational toxin has been well studied. Exposure can fairly easily be defected by analysis of cadmium in biological material. Different routes of cadmium uptake, such as via airborne particles cigarette smoke or contaminated food, have been identified. Urinary concentrations associated with renal effects vary, depending on urinary marker of effect and are as low as 2 mu g cadmium/g creatinine. Different segments of the nephron are affected by cadmium. Urinary enzymes and serum derived proteins mainly low-molecular weight proteins as well as eicosanoids or glycosaminoglycans are among the tubular or glomerular markers of effect. Predisposing factors, such as smoking, dietary habits and low body iron stores have been described It is concluded that even for low level cadmium exposureeffects can be detected with sensitive diagnostic tools.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/10/20 alle ore 23:47:12