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Titolo:
New polyazamacrocycle-nucleoside conjugates : Synthesis, anti-HIV evaluation and interaction with CXCR-4 coreceptor
Autore:
Dessolin, J; Galea, P; Vlieghe, P; Chermann, JC; Kraus, JL;
Indirizzi:
Univ Mediterranee, Fac Sci Luminy, Lab Chim Biomol, F-13288 Marseille 9, France Univ Mediterranee Marseille France 9 Biomol, F-13288 Marseille 9, France INSERM, Retrovirus & Maladies Assoc U322, F-13273 Marseille, France INSERM Marseille France F-13273 es Assoc U322, F-13273 Marseille, France
Titolo Testata:
NUCLEOSIDES & NUCLEOTIDES
fascicolo: 4-5, volume: 18, anno: 1999,
pagine: 881 - 882
SICI:
0732-8311(1999)18:4-5<881:NPC:SA>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
3
Recensione:
Indirizzi per estratti:
Indirizzo: Kraus, JL Univ Mediterranee, Fac Sci Luminy, Lab Chim Biomol, Case 901,163Ave Luminy, F-13288 Marseille 9, France Univ Mediterranee Case 901,163 AveLuminy Marseille France 9 ce
Citazione:
J. Dessolin et al., "New polyazamacrocycle-nucleoside conjugates : Synthesis, anti-HIV evaluation and interaction with CXCR-4 coreceptor", NUCLEOS NUC, 18(4-5), 1999, pp. 881-882

Abstract

We report the synthesis of new conjugates that incorporate in their structure bis-tetraazamacrocycle coupled with AZT via enzymolabile bond. Two series of bis-polyazamacrocycles-AZT conjugates were designed, synthesized and evaluated for their antiviral effect in vitro as well as their capability to bind to CXCR-4 coreceptor.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 11:25:54