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Titolo:
Synthesis and receptor affinity of polysubstituted adenosines
Autore:
Vittori, S; Camaioni, E; Costanzi, S; Volpini, R; Klotz, KN; Cristalli, G;
Indirizzi:
Univ Camerino, Dipartimento Sci Chim, I-62032 Camerino, MC, Italy Univ Camerino Camerino MC Italy I-62032 Chim, I-62032 Camerino, MC, Italy Univ Wurzburg, Inst Pharmakol, D-97078 Wurzburg, Germany Univ Wurzburg Wurzburg Germany D-97078 rmakol, D-97078 Wurzburg, Germany
Titolo Testata:
NUCLEOSIDES & NUCLEOTIDES
fascicolo: 4-5, volume: 18, anno: 1999,
pagine: 739 - 740
SICI:
0732-8311(1999)18:4-5<739:SARAOP>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
2-ALKYNYL DERIVATIVES; SELECTIVE AGONISTS; ADENOSINE-5'-N-ETHYLURONAMIDE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
5
Recensione:
Indirizzi per estratti:
Indirizzo: Vittori, S Univ Camerino, Dipartimento Sci Chim, Via S Agostino 1, I-62032Camerino, MC, Italy Univ Camerino Via S Agostino 1 Camerino MC Italy I-62032 Italy
Citazione:
S. Vittori et al., "Synthesis and receptor affinity of polysubstituted adenosines", NUCLEOS NUC, 18(4-5), 1999, pp. 739-740

Abstract

In a search for potent and selective adenosine agonists it has been found that 2-hexynyladenosine-5'-N-ethyluronamide (HENECA) displays high affinityat rat A(2A) receptor combined with a good A(2A) vs A(1) selectivity. The finding that HENECA shows good affinity also for A(3) receptors prompted usto investigate the effect of various substituents in different positions of this molecule.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 10:52:12