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Titolo:
Juxtaposed microsatellite systems as diagnostic markers for admixture: Theoretical aspects
Autore:
Estoup, A; Cornuet, JM; Rousset, F; Guyomard, R;
Indirizzi:
Inst Natl Rech Agron, Lab Genet Poissons, Jouy En Josas, France Inst Natl Rech Agron Jouy En Josas France issons, Jouy En Josas, France Inst Natl Rech Agron, Unite Rech Lutte Biol, Lab Modelisat & Biol Evolut, Montpellier, France Inst Natl Rech Agron Montpellier France iol Evolut, Montpellier, France CNRS, Lab Genet & Environm, Unite Mixte Rech, Montpellier, France CNRS Montpellier France Environm, Unite Mixte Rech, Montpellier, France
Titolo Testata:
MOLECULAR BIOLOGY AND EVOLUTION
fascicolo: 7, volume: 16, anno: 1999,
pagine: 898 - 908
SICI:
0737-4038(199907)16:7<898:JMSADM>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
TROUT SALMO-TRUTTA; APIS-MELLIFERA L; POLYMORPHIC MICROSATELLITES; GENETIC-MAP; ALLELE SIZE; DIFFERENTIATION; LOCI; MUTATION; DNA; INTROGRESSION;
Keywords:
diagnostic marker; genetic admixture; homoplasy; hybridization; linked markers; microsatellites;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
46
Recensione:
Indirizzi per estratti:
Indirizzo: Estoup, A Univ Queensland, Dept Zool, St Lucia, Qld 4072, Australia Univ Queensland St Lucia Qld Australia 4072 Qld 4072, Australia
Citazione:
A. Estoup et al., "Juxtaposed microsatellite systems as diagnostic markers for admixture: Theoretical aspects", MOL BIOL EV, 16(7), 1999, pp. 898-908

Abstract

Two populations which have diverged from an ancestral population may come back into contact due to human action via stocking or introduction programs. We report here a method to measure genetic admixture in such situations based on juxtaposed microsatellite systems (JMSs). A JMS is composed of two microsatellite repeat arrays separated by a sequence of less than 200 bp. The advantage of a JMS stems from the superior genealogical information carried by the two microsatellite sites to that carried by just one. If five assumptions are fulfilled, JMSs provide reliable diagnostic markers which eliminate the need to know the genetic structure of the native population in the absence of admixture. Simulations show that optimal features at both microsatellite sites of the JMS are the occurrence of multistep mutations, moderately high mutation rates, and limited allele size constraints. Optimal demographic features include a relatively large number of generations since the separation of the alien and native populations and small population sizes,especially for the alien population. Substantial sampling of the alien population is also necessary.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/09/20 alle ore 13:32:40