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Titolo:
SERUM TSH DETERMINATION COMBINED WITH FIN E-NEEDLE ASPIRATION VERSUS FIRST-LINE SCINTIGRAPHY IN THE DIAGNOSIS OF THYROID-NODULES - A PROSPECTIVE-STUDY
Autore:
TOURNIAIRE J; NICOLAS MH; PAULIN C; FLEURY MC; DUTRIEUXBERGER N; CHARRIE A; BERNARD MH;
Indirizzi:
HOP ANTIQUAILLE,CLIN ENDOCRINOL,NUCL MED LAB F-69321 LYON 5 FRANCE UNIV LYON 1,CLIN ENDOCRINOL F-69365 LYON FRANCE CTR HOSP LYON SUD,LAB CYTOL LYON FRANCE HOP HOTEL DIEU,LAB ANAT PATHOL LYON FRANCE
Titolo Testata:
La Presse medicale
fascicolo: 16, volume: 26, anno: 1997,
pagine: 752 - 755
SICI:
0755-4982(1997)26:16<752:STDCWF>2.0.ZU;2-N
Fonte:
ISI
Lingua:
FRE
Soggetto:
BIOPSY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
9
Recensione:
Indirizzi per estratti:
Citazione:
J. Tourniaire et al., "SERUM TSH DETERMINATION COMBINED WITH FIN E-NEEDLE ASPIRATION VERSUS FIRST-LINE SCINTIGRAPHY IN THE DIAGNOSIS OF THYROID-NODULES - A PROSPECTIVE-STUDY", La Presse medicale, 26(16), 1997, pp. 752-755

Abstract

OBJECTIVES: Fine-needle aspiration (FNA) is now considered as the first-line investigation for the diagnosis of thyroid nodules. We searched fora more accurate and cost-effective methodology as this technique.fails to recognized hot nodules, frequent in certain countries. PATIENTS AND METHODS: A prospective study was conducted in 150 patients to compare two diagnostic procedures: scintigraphy first combined with FNA in case of cold nodules versus TSH measurement plus FNA when TSH wasnot depressed. The results were subjected to cost/benefit analysis. RESULTS: Cystic nodules were found in 28 cases (including 3 hyperfunctionning nodules, with 5 suspicious smears (1 carcinoma). FNA was non-diagnostic in 26 patients; 12 were operated on (1 carcinoma), 14 had further FNA (5 suspicious, 9 benign). Altogether 56 nodules were removed,for toxic adenoma (n = 5), for suspicious (n = 21) or malignant (n = 12) smear, or on personal (n = 18) demand; 16 carcinomas were found (2medullary, 13 capillary, 1 follicular carcinomas). With scintigraphy first the cost was 787 French francs (FF) per patient With TSH measurement and FNA, the cost was 554 FF per patient In both cases, the same number of carcinomas were removed, and all the hot nodules (11 including 5 toxic adenomas) were detected. CONCLUSION: Serum TSH measurement,with scintigraphy if TSH is low, and FNA in all the other cases, is accurate and more cost-effective than scintigraphy as a first-line investigation for the diagnosis of thyroid nodule.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/09/20 alle ore 00:11:56