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Titolo:
Malignant Brenner tumors of the ovary and tumor markers: Case reports
Autore:
Yamamoto, R; Fujita, M; Kuwabara, M; Sogame, M; Ebina, Y; Sakuragi, N; Kato, H; Fujimoto, S;
Indirizzi:
Hokkaido Univ, Sch Med, Dept Obstet & Gynecol, Kita Ku, Sapporo, Hokkaido 0608638, Japan Hokkaido Univ Sapporo Hokkaido Japan 0608638 oro, Hokkaido 0608638, Japan
Titolo Testata:
JAPANESE JOURNAL OF CLINICAL ONCOLOGY
fascicolo: 6, volume: 29, anno: 1999,
pagine: 308 - 313
SICI:
0368-2811(199906)29:6<308:MBTOTO>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROGESTERONE RECEPTORS; CELL-CARCINOMA; ANTIGEN; ESTROGEN; CANCER;
Keywords:
malignant Brenner tumor; immunohistochemistry; CA125; CA72-4; SCC;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Yamamoto, R Hokkaido Univ, Sch Med, Dept Obstet & Gynecol, Kita Ku, Kita 15,Nishi 7, Sapporo, Hokkaido 0608638, Japan Hokkaido Univ Kita 15,Nishi 7 Sapporo Hokkaido Japan 0608638 n
Citazione:
R. Yamamoto et al., "Malignant Brenner tumors of the ovary and tumor markers: Case reports", JPN J CLIN, 29(6), 1999, pp. 308-313

Abstract

We investigated the tumor marker for malignant Brenner tumors, which had not been established because of the rarity and variable histological criteria. Representative areas of two cases of malignant Brenner tumor were investigated by means of the peroxidase-antiperoxidase method using monoclonal antibody to CA125 and CA72-4 antigen and the streptavidin-biotin immunoperoxidase complex method using monoclonal antibody to SCC antigen. Based on clinical course and immunohistochemical studies, serum CA125 and CA72-4 for Case 1 and SCC and CA72-4 for Case 2 were appropriate tumor markers for the establishment of the extent of tumor burden before treatment and to monitor the response to therapy. The discrepancy of the tumor markers of the two present cases is considered to be a reflection of the difference in the malignant component of these cases. However, serum CA72-4 was an appropriate tumor marker for both malignant Brenner tumors.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 23:45:31