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Titolo:
Perioperative catecholamine changes in cardiac risk patients
Autore:
Sametz, W; Metzler, H; Gries, M; Porta, S; Sadjak, A; Supanz, S; Juan, H;
Indirizzi:
Graz Univ, Dept Biomed Res, A-8036 Graz, Austria Graz Univ Graz Austria A-8036 niv, Dept Biomed Res, A-8036 Graz, Austria Graz Univ, Dept Anaesthesiol, Graz, Austria Graz Univ Graz AustriaGraz Univ, Dept Anaesthesiol, Graz, Austria Graz Univ, Dept Gen & Expt Pathol, Graz, Austria Graz Univ Graz AustriaGraz Univ, Dept Gen & Expt Pathol, Graz, Austria
Titolo Testata:
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
fascicolo: 7, volume: 29, anno: 1999,
pagine: 582 - 587
SICI:
0014-2972(199907)29:7<582:PCCICR>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; NONCARDIAC SURGERY; TROPONIN-I; CONJUGATED CATECHOLAMINES; PLASMA-CATECHOLAMINES; VASCULAR-SURGERY; UNSTABLE ANGINA; ISCHEMIA; SEVERITY; AGGREGATION;
Keywords:
catecholamines; troponins; post-operative cardiac complications;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Sametz, W Graz Univ, Dept Biomed Res, Roseggerweg 48, A-8036 Graz, AustriaGraz Univ Roseggerweg 48 Graz Austria A-8036 8036 Graz, Austria
Citazione:
W. Sametz et al., "Perioperative catecholamine changes in cardiac risk patients", EUR J CL IN, 29(7), 1999, pp. 582-587

Abstract

Background It has previously been found that in cardiac risk patients undergoing noncardiac surgery post-operative cardiac complications are correlated with high post-operative serum levels of troponin T (TNT) and troponin I(TNI). We investigated whether perioperative changes in the release of free (fCAs) and conjugated catecholamines (cCAs) correlate with the increased serum level of TN (TNI). Materials and methods Plasma. levels of CAs were determined in 28 patientsat risk for or with definite coronary artery disease. Blood sampling was performed in the morning on the day before surgery, on the day of surgery before induction of anaesthesia and until the fifth post-operative day Tor measurement of CAs by high-performance liquid chromatography. Results The plasma concentrations of free and conjugated noradrenaline (fTA and cNA) as well as of free and conjugated adrenaline (fA and cA) were increased significantly in TN up arrow patients post-operatively. The plasma levels of free as well as df conjugated NA and A TN up arrow patients were significantly higher than in TN0 patients over the whole post-operative period. Conclusion This study demonstrates that increased post-operative release of fNA and EA as well as of cNA and cA correlates with high post-operative serum levels of troponins in cardiac risk patients undergoing non-cardiac surgery.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 00:07:00