Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Orphanin FQ antagonizes the analgesic effect of 5-HT in rat brain
Autore:
Wang, Y; Zhang, AX; Xu, W; Chang, JK; Han, JS;
Indirizzi:
Beijing Med Univ, Neurosci Res Inst, Beijing 100083, Peoples R China Beijing Med Univ Beijing Peoples R China 100083 100083, Peoples R China Changzhi Med Coll, Dept Physiol, Shanxi 004600, Peoples R China Changzhi Med Coll Shanxi Peoples R China 004600 004600, Peoples R China Phoenix Pharmaceut Inc, Mt View, CA 94043 USA Phoenix Pharmaceut Inc Mt View CA USA 94043 ut Inc, Mt View, CA 94043 USA
Titolo Testata:
CHINESE SCIENCE BULLETIN
fascicolo: 9, volume: 44, anno: 1999,
pagine: 793 - 795
SICI:
1001-6538(199905)44:9<793:OFATAE>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Keywords:
orphanin FQ; 5-HT; analgesia; brain; rat;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
6
Recensione:
Indirizzi per estratti:
Indirizzo: Wang, Y Beijing Med Univ, Neurosci Res Inst, Beijing 100083, Peoples R China Beijing Med Univ Beijing Peoples R China 100083 Peoples R China
Citazione:
Y. Wang et al., "Orphanin FQ antagonizes the analgesic effect of 5-HT in rat brain", CHIN SCI B, 44(9), 1999, pp. 793-795

Abstract

Orphanin FQ (OFQ) is a new modulatory peptide which was found in 1994. It mediates in morphine analgesia and electroacupuncture analgesia. The interaction between OFQ and 5-hydroxytryptamine (5-HT) on analgesia was observed using the method of intracerebroventricular microinjection. The results showed that cumulative i.c.v. administration of gradually increasing doses of 5-HT produced a dose-dependent analgesia, and administration of different doses of OFQ separateness had no significant effect on tail flick latency, but 1 or 10 mu g OFQ could reverse the analgesia induced by 5-HT, suggestingthat OFQ could antagonize the analgesia induced by 5-HT in rat brain.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 15:24:28