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Titolo:
Quantitative non-radioactive in situ hybridization study of GAP-43 and SCG10 mRNAs in the cerebral cortex of adult and infant macaque monkeys
Autore:
Higo, N; Oishi, T; Yamashita, A; Matsuda, K; Hayashi, M;
Indirizzi:
Electrotech Lab, Informat Sci Div, Neurosci Sect, Ibaraki, Osaka 3058568, Japan Electrotech Lab Ibaraki Osaka Japan 3058568 Ibaraki, Osaka 3058568, Japan Univ Tsukuba, Sch Med, Dept Physiol, Ibaraki, Osaka 3050006, Japan Univ Tsukuba Ibaraki Osaka Japan 3050006 l, Ibaraki, Osaka 3050006, Japan Nihon Univ, Sch Med, Dept Anat, Itabashi Ku, Tokyo 1738610, Japan Nihon Univ Tokyo Japan 1738610 t Anat, Itabashi Ku, Tokyo 1738610, Japan Kyoto Univ, Inst Primate Res, Dept Cellular & Mol Biol, Aichi 4840081, Japan Kyoto Univ Aichi Japan 4840081 Cellular & Mol Biol, Aichi 4840081, Japan
Titolo Testata:
CEREBRAL CORTEX
fascicolo: 4, volume: 9, anno: 1999,
pagine: 317 - 331
SICI:
1047-3211(199906)9:4<317:QNISHS>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
GROWTH-ASSOCIATED PROTEIN; MESSENGER-RNA LOCALIZATION; LOCAL CIRCUIT NEURONS; SENSORY-MOTOR CORTEX; VISUAL-CORTEX; RHESUS-MONKEY; PREFRONTAL CORTEX; GENE-EXPRESSION; STRIATE CORTEX; MEYNERT CELLS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
89
Recensione:
Indirizzi per estratti:
Indirizzo: Oishi, T Electrotech Lab, Informat Sci Div, Neurosci Sect, Ibaraki, Osaka 3058568, Japan Electrotech Lab Ibaraki Osaka Japan 3058568 Osaka 3058568, Japan
Citazione:
N. Higo et al., "Quantitative non-radioactive in situ hybridization study of GAP-43 and SCG10 mRNAs in the cerebral cortex of adult and infant macaque monkeys", CEREB CORT, 9(4), 1999, pp. 317-331

Abstract

We performed non-radioactive in situ hybridization histochemistry in several areas that include both the association areas and the lower sensory areas of monkey cerebral cortex, and investigated the localization of neurons expressing two growth-associated proteins: GAP-43 and SCG10. Both GAP43 and SCG10 mRNAs were observed in both pyramidal and non-pyramidal neurons. Prominent hybridiza tion signals for GAP-43 mRNA were observed in layers II-VI of the adult association areas: the prefrontal areas (FD), the temporal (TE) and the parietal (PG) association areas. The signals for GAP43 mRNA were weak in layers I-III of the adult primary somatosensory area (PB) and primary (OC) and secondary (OB) visual areas, and cells with prominent signals were observed in layers IV-VI. The prominent signals for SCG10 mRNA were observed in layers IV-VI of all areas examined. These results suggest that theexpression pattern of GAP43 mRNA, but not that of SCG10 mRNA, may be related to the functional difference between association and lower sensory areasof adult cortex. In the infant cortex (postnatal days 2, 8 and 31), the signals for both mRNAs were intense in layers II-VI of all areas. Therefore, layer-specific expressions of GAP43 and SCG10 mRNAs are established after the first postnatal month.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 03:29:25