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Titolo:
Oral contraceptive use and risk of endometriosis
Autore:
Parazzini, F; Di Cintio, E; Chatenoud, L; Moroni, S; Mezzanotte, C; Crosignani, G; Ardovino, I; Struzziero, E; Zanardi, E; Pungetti, D; Mais, V; Ajossa, S; Mignemi, G; Di Leo, L; Bianchi, A; Campobaso, C; Scarselli, G; Bracco, G; Capetta, P; Bertulessi, C; Moroni, S; Mazza, P; Vercellini, P; Modena, AB; Cirziz, E; Casa, A; Primicerio, M; Massobrio, M; Ansaldi, C; Trossarelli, G; Gervasi, MT; Marsoni, V; Guaschino, S; Troiano, L; Ricci, G; Beretta, P; Franchi, M;
Indirizzi:
Ist Ric Farmacol Mario Negri, I-20157 Milan, Italy Ist Ric Farmacol Mario Negri Milan Italy I-20157 i, I-20157 Milan, Italy
Titolo Testata:
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
fascicolo: 7, volume: 106, anno: 1999,
pagine: 695 - 699
SICI:
1470-0328(199907)106:7<695:OCUARO>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
EPIDEMIOLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Parazzini, F Ist Ric Farmacol Mario Negri, Via Eritrea 62, I-20157 Milan, Italy Ist Ric Farmacol Mario Negri Via Eritrea 62 Milan Italy I-20157
Citazione:
F. Parazzini et al., "Oral contraceptive use and risk of endometriosis", BR J OBST G, 106(7), 1999, pp. 695-699

Abstract

Objective To analyse the association between use of oral contraception andrisk of pelvic endometriosis. Design We compared use of oral contraception in women with and without endometriosis. Participants Eligible for the study were women with primary or secondary infertility (n = 393) or chronic pelvic pain (n = 424), requiring laparoscopy, consecutively observed between September 1995 and January 1996 in 15 obstetrics and gynaecology departments in Italy. Results Out of the 817 women included in the study, 345 had a diagnosis ofendometriosis; 164 (47.5%) women with endometriosis and 139 (29.4%) without the disease reported ever using oral contraception. In comparison with never users the estimated odds ratios (OR) of endometriosis were 1.8 (95% CI 1.0-3.3) in current users and 1.6 (95% CI 1.1-2.4) in ex-users. No clear relation emerged between duration of oral contraceptive use and risk of endometriosis. In comparison with never users, the OR was 1.8 (95% CI 1.1-3.0) for women reporting their last use of oral contraception < 5 years before interview and 15 (95% CI 0.9-2.5) for those reporting their last use greater than or equal to 5 years before interview. Conclusions The study suggests that oral contraception is associated with an increased risk of endometriosis but this finding is based on a selected population and cannot generalised to all women with endometriosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 17:43:58