Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Variability in annual mini-mental state examination score in patients withprobable Alzheimer disease - A clinical perspective of data from the consortium to establish a registry for Alzheimer's disease
Autore:
Clark, CM; Sheppard, L; Fillenbaum, GG; Galasko, D; Morris, JC; Koss, E; Mohs, R; Heyman, A;
Indirizzi:
Univ Penn, Dept Neurol, Alzheimers Dis Ctr, Philadelphia, PA 19104 USA Univ Penn Philadelphia PA USA 19104 s Dis Ctr, Philadelphia, PA 19104 USA Univ Penn, Inst Aging, Philadelphia, PA 19104 USA Univ Penn Philadelphia PA USA 19104 nst Aging, Philadelphia, PA 19104 USA Univ Washington, Dept Biostat, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 Dept Biostat, Seattle, WA 98195 USA Univ Washington, Dept Environm Hlth, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 Environm Hlth, Seattle, WA 98195 USA Univ Washington, Alzheimers Dis Res Ctr, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 s Dis Res Ctr, Seattle, WA 98195 USA Duke Univ, Med Ctr, Ctr Study Aging & Human Dev, Durham, NC 27710 USA DukeUniv Durham NC USA 27710 udy Aging & Human Dev, Durham, NC 27710 USA Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA Duke Univ Durham NC USA 27710 iv, Med Ctr, Dept Med, Durham, NC 27710 USA Univ Calif San Diego, Dept Neurol, San Diego, CA 92103 USA Univ Calif San Diego San Diego CA USA 92103 urol, San Diego, CA 92103 USA Washington Univ, Dept Neurol, St Louis, MO USA Washington Univ St Louis MO USA gton Univ, Dept Neurol, St Louis, MO USA Case Western Reserve Univ Hosp, Dept Neurol, Cleveland, OH 44106 USA Case Western Reserve Univ Hosp Cleveland OH USA 44106 eland, OH 44106 USA Mt Sinai Bronx VA Hosp, Dept Psychiat, New York, NY USA Mt Sinai Bronx VA Hosp New York NY USA , Dept Psychiat, New York, NY USA
Titolo Testata:
ARCHIVES OF NEUROLOGY
fascicolo: 7, volume: 56, anno: 1999,
pagine: 857 - 862
SICI:
0003-9942(199907)56:7<857:VIAMSE>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
SENILE DEMENTIA; SCREENING-TESTS; RELIABILITY; IMPAIRMENT; RATES; CERAD; PROGRESSION; VALIDITY; HEALTH; SCALE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Clark, CM Univ Penn, Dept Neurol, Alzheimers Dis Ctr, 3615 Chestnut St, Philadelphia, PA 19104 USA Univ Penn 3615 Chestnut St Philadelphia PA USA 19104 A 19104 USA
Citazione:
C.M. Clark et al., "Variability in annual mini-mental state examination score in patients withprobable Alzheimer disease - A clinical perspective of data from the consortium to establish a registry for Alzheimer's disease", ARCH NEUROL, 56(7), 1999, pp. 857-862

Abstract

Objective: To determine the variability in annual Mini-Mental State Examination scores of patients with Alzheimer disease enrolled in the Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Patients: A total of 372 patients with probable Alzheimer disease with 1 or more years of follow-up. Setting: Twenty-one CERAD clinical sites throughout the United States. Results: An average annual decline of 3.4 points in CERAD patients returning for longitudinal, reassessments was close to the SD of the measurement error of 2.8 points for the Mini-Mental State Examination. There was wide variability in individual rates of decline. Even with 4 years of follow-up, 15.8% of the patients had no clinically meaningful decline in Mini-Mental State Examination score (defined as a change in initial score >3, ie, 1 SD ofmeasurement error). Validity of measurements of the rate of change in Mini-Mental State Examination scores improved with longer observation intervalsand was reliable for most patients when observations were separated by 3 or more years. Conclusions: Although the Mini-Mental State Examination is a useful screening instrument to assess level of cognitive function, it has limited value in measuring the progression of Alzheimer disease in individual patients for periods less than 3 years because of a large measurement error and substantial variation in change in annual score.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 20:10:56