Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Amygdala co-ordinates sudden falls in ear pinna blood flow in response to unconditioned salient stimuli in conscious rabbits
Autore:
Yu, YH; Blessing, WW;
Indirizzi:
Flinders Univ S Australia, Ctr Neurosci, Dept Physiol, Bedford Pk, SA 5042, Australia Flinders Univ S Australia Bedford Pk SA Australia 5042 SA 5042, Australia Flinders Univ S Australia, Ctr Neurosci, Dept Med, Bedford Pk, SA 5042, Australia Flinders Univ S Australia Bedford Pk SA Australia 5042 SA 5042, Australia
Titolo Testata:
NEUROSCIENCE
fascicolo: 1, volume: 93, anno: 1999,
pagine: 135 - 141
SICI:
0306-4522(1999)93:1<135:ACSFIE>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
MEDIAL GENICULATE-BODY; IBOTENIC ACID LESIONS; CENTRAL NUCLEUS; EMOTIONAL RESPONSES; DOUBLE DISSOCIATION; ACOUSTIC STIMULI; CONDITIONED FEAR; NEURONS; ACQUISITION; BRADYCARDIA;
Keywords:
cutaneous blood flow; amygdala; tetrodotoxin; alerting responses; ear pinna; stress;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Blessing, WW Flinders Univ S Australia, Ctr Neurosci, Dept Physiol, Bedford Pk, SA 5042, Australia Flinders Univ S Australia Bedford Pk SA Australia5042 ralia
Citazione:
Y.H. Yu e W.W. Blessing, "Amygdala co-ordinates sudden falls in ear pinna blood flow in response to unconditioned salient stimuli in conscious rabbits", NEUROSCIENC, 93(1), 1999, pp. 135-141

Abstract

Tetrodotoxin (10 pmol in 300 nl of Ringer), injected bilaterally into the region of the amygdala in conscious rabbits, virtually abolished the suddenfalls in ear pinna blood flow that normally occur in response to salient environmental stimuli (touching the animal's fur, slightly moving its cage, or applying or removing a drape covering the cage). Time spent at 0-20% of maximum flow values during a 10 min observation period, commencing 15 min after injection of tetrodotoxin, significantly decreased compared with the pre-injection control period (30 +/- 14 s compared with 286 +/- 24 s, P<0.01, n=8 rabbits) and the time spent at 70-100% of maximum flow values significantly increased (521 +/- 36 s compared with 127 +/-29 s, P<0.01). Vehicle was injected on the day before tetrodotoxin injections in four of eight rabbits and on the day after tetrodotoxin injections in the other four rabbits, in a counterbalanced design. Rabbits fully recovered from the effects of tetrodotoxin in one day. Vehicle did not significantly affect the time spent at different flow percentage values. Falls in ear blood flow elicited by noxious stimuli (ear pinch, inhalation of formaldehyde vapor) occurred in anormal pattern after tetrodotoxin. Amygdaloid circuitry is thus necessary for the production of falls in ear pinna blood flow that occur in response to unconditioned non-noxious stimuli, but not for the falls that occur in response to unconditioned noxious stimuli in rabbits. In humans, the amygdaloid region may also be involved in co-ordinating falls in cutaneous blood flow occurring in response to salient or anxiety-evoking stimuli. Thus, discovery of the neural pathways by which amygdaloid circuitry alters ear pinna blood flow in rabbits may elucidate the manner in which similar cardiovascular changes occur in humans duringanxiety reactions. (C) 1999 IBRO. Published by Elsevier Science Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 11:29:23