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Titolo:
Towards the neural basis for hypersociability in a genetic syndrome
Autore:
Bellugi, U; Adolphs, R; Cassady, C; Chiles, M;
Indirizzi:
Salk Inst Biol Studies, Cognit Neurosci Lab, La Jolla, CA 92037 USA Salk Inst Biol Studies La Jolla CA USA 92037 Lab, La Jolla, CA 92037 USA Univ Iowa, Dept Neurol, Div Cognit Neurosci, Iowa City, IA 52242 USA Univ Iowa Iowa City IA USA 52242 Cognit Neurosci, Iowa City, IA 52242 USA
Titolo Testata:
NEUROREPORT
fascicolo: 8, volume: 10, anno: 1999,
pagine: 1653 - 1657
SICI:
0959-4965(19990603)10:8<1653:TTNBFH>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
WILLIAMS-SYNDROME; HUMAN AMYGDALA;
Keywords:
dissociations in cognitive functions; experimental study of approachability; genetic disorder; neural and genetic basis of social behavior; social behavior; Williams syndrome;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Bellugi, U Salk Inst Biol Studies, Cognit Neurosci Lab, 10010 N Torrey Pines Rd, La Jolla, CA 92037 USA Salk Inst Biol Studies 10010 N Torrey Pines Rd La Jolla CA USA 92037
Citazione:
U. Bellugi et al., "Towards the neural basis for hypersociability in a genetic syndrome", NEUROREPORT, 10(8), 1999, pp. 1653-1657

Abstract

WILLIAMS syndrome (WMS), a rare disorder with a distinctive profile of medical, psychological, neurophysiological and neuroanatomical characteristics, results from hemizygous deletion of about 20 genes. The phenotype exhibits specific dissociations in higher cognitive functions: general cognitive deficits but spared linguistic abilities; extreme spatial cognitive deficits, but intact face processing. Of special, interest is an unusual social phenotype in WMS: an overly friendly, engaging personality and excessive sociability with strangers. In this first experimental study of social behavior in WMS, we report that WMS subjects show an abnormal positive bias in theirsocial judgments of unfamiliar individuals, consistent with their behaviorin real life. Our findings contribute to an understanding of the neural and genetic bases of human social behavior. NeuroReport 10:1653-1657 (C) 1999Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 09:56:59