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Titolo:
The causative role of physiological parameters on cognitive functions of geriatric patients after regional- or general anaesthesia
Autore:
Dahn, J; Oster, M; Moltner, A; Wohrle, C; Ratzer-Frey, A; van Ackern, K; Holzl, R; Segiet, W;
Indirizzi:
Univ Heidelberg, Klinikum Mannheim, Klinikum Mannheim GGmBH, Inst Anasthesiol & Operat Intensivmed, D-68167 Mannheim, Germany Univ Heidelberg Mannheim Germany D-68167 vmed, D-68167 Mannheim, Germany Univ Heidelberg, Klinikum Mannheim, Klinikum Mannheim GGmBH, Neurol Klin, D-68167 Mannheim, Germany Univ Heidelberg Mannheim Germany D-68167 Klin, D-68167 Mannheim, Germany Univ Mannheim, Lab Klin Psychophysiol, Otto Selz Inst, D-68167 Mannheim, Germany Univ Mannheim Mannheim Germany D-68167 z Inst, D-68167 Mannheim, Germany
Titolo Testata:
ANAESTHESIST
fascicolo: 6, volume: 48, anno: 1999,
pagine: 379 - 386
SICI:
0003-2417(199906)48:6<379:TCROPP>2.0.ZU;2-1
Fonte:
ISI
Lingua:
GER
Soggetto:
ELDERLY PATIENTS; ANESTHESIA; RECOVERY; ISOFLURANE; CONFUSION; HYPOXEMIA; TRIAL; HIP;
Keywords:
geriatric patients; anaesthesia; cognitive functions; physiological parameters; hip arthroplasty;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Dahn, J Univ Heidelberg, Klinikum Mannheim, Klinikum Mannheim GGmBH, Inst Anasthesiol & Operat Intensivmed, Theodor Kutzer Ufer 1-3, D-68167 Mannheim, Germany Univ Heidelberg Theodor Kutzer Ufer 1-3 Mannheim Germany D-68167
Citazione:
J. Dahn et al., "The causative role of physiological parameters on cognitive functions of geriatric patients after regional- or general anaesthesia", ANAESTHESIS, 48(6), 1999, pp. 379-386

Abstract

Objective: The aim of the present study was to show the influence of the parameters of gas exchange (arterial oxygen pressure paO(2), arterial oxygensaturation SatO(2)) and haemodynamics (arterial systolic and mean blood pressure RRs and MAP) on the restitution of cognitive functions in geriatric patients scheduled for elective hip arthroplasty. Methods: A total of 30 patients (70 years, ASA II) were randomized to be operated either in regional anaesthesia (n=15) or general anaesthesia (n=15). PaO2 (by capillary blood gas analysis), RRs and MAP (by oscillometry) were measured 15 and 90 minutes after arrival in the recovery unit (t1 and t2), 24 and 72 hours postoperatively (t3 and t4),and cognitive functions were tested. Intraoperatively, throughout the day and the first night after surgery we measured satO(2) by continous pulse oximetry. We recorded MAP and RRs by oscillometry every 3 minutes during the operation and every 15 minutesfor the rest of that day and night. Results: The parameters of gas exchange and haemodynamics did not differ among the groups. PaO2 was significantly reduced in both groups compared to baseline 24 hours postoperatively (t3) and remained low until 72 hours postoperatively (t4). Nearly all cognitive functions were significantly reducedin both groups compared to baseline 15 and 90 minutes after arrival in therecovery unit (t1 and t2), but recovered on the first post operative day (t3). Both groups kept deficits in verbal memory and reading capacity up to the third postoperative day (t1). There was no correlation between the physiological parameters and the restitution of the tested cognitive functions. Conclusion: The restitution of cognitive functions during the first three postoperative days in geriatric patients scheduled for elective hip surgerydoes not depend on the anaesthetic technique. According to our results regional anaesthesia does not show any advantage for geriatric patients undergoing elective hip arthroplasty.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 02:36:20