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Titolo:
Discrepancies between reported food intolerance and sensitization test findings in irritable bowel syndrome patients
Autore:
Dainese, R; Galliani, EA; De Lazzari, F; Di Leo, V; Naccarato, R;
Indirizzi:
Univ Padua, Dept Surg & Gastroenterol Sci, Gastroenterol Unit, Padua, Italy Univ Padua Padua Italy troenterol Sci, Gastroenterol Unit, Padua, Italy
Titolo Testata:
AMERICAN JOURNAL OF GASTROENTEROLOGY
fascicolo: 7, volume: 94, anno: 1999,
pagine: 1892 - 1897
SICI:
0002-9270(199907)94:7<1892:DBRFIA>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
HISTAMINE-RELEASE; COLONIC MUCOSA; DIARRHEIC TYPE; ALLERGY; HYPERSENSITIVITY; DISEASE; SYMPTOMS; BRAIN; IGE; GUT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: De Lazzari, F Div Gastroenterol, Via Giustiniani 2, I-35128 Padua, Italy Div Gastroenterol Via Giustiniani 2 Padua Italy I-35128 aly
Citazione:
R. Dainese et al., "Discrepancies between reported food intolerance and sensitization test findings in irritable bowel syndrome patients", AM J GASTRO, 94(7), 1999, pp. 1892-1897

Abstract

OBJECTIVE: irritable bowel syndrome (IBS) is a common gastrointestinal disorder with clinical signs typical of "intestinal" food allergies or intolerance. The aim of this study was to characterize the clinical features or IBS patients suspected of suffering from adverse reactions to food. METHODS: The study involved 128 consecutive IBS patients divided into fourgroups according to their main symptom on presentation at our outpatient clinic. A detailed medical history was recorded, paying particular attentionto any allergies and reported intolerance to food. Each patient was screened for allergies; intestinal permeability tests was performed in randomly selected patients from different groups. Findings were analyzed using the chi(2) test. RESULTS: Adverse reactions to one or more foods were reported by 80 patients (62.5%); skin prick tests (SPT) were positive in 67 patients (52.3%) with no significant differences between patients complaining of different symptoms. Patients who reported a food intolerance had more positive SPTs than those who did not (47 of 80 [58.7%] vs 20 of 48 [41.7%]); this difference was not statistically significant, although it suggests a trend (p < 0.0610). There was little consistency between the specific foods reported to causeintolerance and those resulting from the tests (11 of 80 patients, 13.7%). The intestinal permeability test was normal in 29 of 33 patients (87.9%). CONCLUSIONS: More than 50% of IBS patients were found sensitized to some food or inhalant without any typical clinical signs. Patients were unable toidentify potentially offending foods. The lack of a correlation between SPT results and reported food allergies needs further investigation to clarify the pathophysiology and improve the diagnosis of intestinal food allergies. (Am J Gastroenterol 1999; 94:1892-1897, (C) 1999 by Am. Cell. of Gastroenterology).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 09:03:13