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Titolo:
A rapid and facile method for the preparation of peptide disulfides
Autore:
Maruyama, T; Ikeo, T; Ueki, M;
Indirizzi:
Toray Res Ctr Inc, Kanagawa 2488555, Japan Toray Res Ctr Inc Kanagawa Japan 2488555 tr Inc, Kanagawa 2488555, Japan Sci Univ Tokyo, Fac Sci, Dept Appl Chem, Shinjuku Ku, Tokyo 1628601, JapanSci Univ Tokyo Tokyo Japan 1628601 em, Shinjuku Ku, Tokyo 1628601, Japan
Titolo Testata:
TETRAHEDRON LETTERS
fascicolo: 27, volume: 40, anno: 1999,
pagine: 5031 - 5034
SICI:
0040-4039(19990702)40:27<5031:ARAFMF>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
FLUORIDE; ANALOGS; BRIDGES; REMOVAL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Physical, Chemical & Earth Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Maruyama, T Toray Res Ctr Inc, Kanagawa 2488555, Japan Toray Res Ctr Inc Kanagawa Japan 2488555 gawa 2488555, Japan
Citazione:
T. Maruyama et al., "A rapid and facile method for the preparation of peptide disulfides", TETRAHEDR L, 40(27), 1999, pp. 5031-5034

Abstract

A selective and efficient method for disulfide bond formation in peptides utilizing carbon tetrachloride in dichloromethane in the presence of tetrabutylammonium fluoride (TBAF) is described. The reaction proceeded rapidly and no side reaction was observed with nucleophilic amino acids such as Met,His,Tyr or Trp. This method has been applied to three model peptides usingsolution and on-the-resin disulfide formation. (C) 1999 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/07/20 alle ore 06:39:30